BACKGROUND This study describes a new method for determining site-specific vascular shear stress using dynamic measures of shear rate and blood viscosity (BV) in the carotid arteries, and examines characteristics of carotid arterial shear stress among patients with lacunar infarction. METHODS Vascular shear stress measurements were conducted in 37 patients (17 lacunar infarction patients and ...

The current study presents the development and implementation of a bespoke experimental technique to generate characterise mode II crack initiation propagation in arterial tissue. begins with demonstration that lap-shear testing tissue results mixed fracture, rather than II. We perform detailed computational design method (which we refer as shear fracture ring test (SFRT)) robustly repeatably a...

Plug failures have been observed in three-sheet spot welds, where the weld nugget did not penetrate into outer sheet. Such solid-state bonds were found to be formed as a result of high contact pressure and temperature during welding. The strength single welds was studied combination (0.61 mm DX54 on two 1.21 DP600) with penetrations thin sheet below 40%. static evaluated by tensile shear, cross...

Multifunctional self-healing composites have great potential in several applications, i.e., from automotive to aerospace. This study examines the behavior of carbon fiber reinforced by depositing jet-spun cyclic olefin copolymer (COC) meshes on dry plies before lamination with epoxy resin (EP). Three different laminates were prepared, including neat EP/CF and two 4 wt.% 8 COC form a network as ...

Once plaques intrude into the lumen, the shear stress they are exposed to alters with hitherto unknown consequences for plaque composition. We investigated the relationship between shear stress and strain, a marker for plaque composition, in human coronary arteries. We imaged 31 plaques in coronary arteries with angiography and intravascular ultrasound. Computational fluid dynamics was used to ...

Matrix resins of carbon fiber-epoxy composites with different numbers of epoxy functional groups were prepared, and their properties were compared to optimize the matrix resin composition. To understand the bonding strengths between the carbon fiber and epoxy resins in monofilaments and micro-sized resin beads, the interfacial shear strength (IFSS) was measured using the microdroplet technique....

Endothelial cells (ECs) sense shear stress and transduce blood flow information into functional responses that play important roles in vascular homeostasis and pathophysiology. A unique feature of shear-stress-sensing is the involvement of many different types of membrane-bound molecules, including receptors, ion channels and adhesion proteins, but the mechanisms remain unknown. Because cell me...

AIM To determine if the internal limiting membrane (ILM) was present in the epiretinal membrane (ERM) when we deliberately tried to perform a "double peel" for macular pucker. METHODS Pars-plana vitrectomy and a "double peel" were carried out. The ERM and ILM were stained with Trypan Blue and peeled separately over the same area. The amount of ERM present in ILM specimens and the amount of IL...