نتایج جستجو برای: interleukin 7 receptor
تعداد نتایج: 1250577 فیلتر نتایج به سال:
Chimeric antigen receptor (CAR)-T cell therapy has impressive efficacy in hematological malignancies, but its application solid tumors remains a challenge. Multiple hurdles associated with the biological and immunological features of currently limit CAR-T cells treatment tumors. Using syngeneic mouse models, we recently reported that engineered to concomitantly produce interleukin (IL)-7 chemok...
Ulcerative colitis is chronic and recurrent disease of the gastrointestinal tract with uncertain etiology and incomplete treatment options. N-methyl-d-aspartate (NMDA) receptor suppression has shown anti-inflammatory effects in vitro and in vivo. The aim of present study was to evaluate the role of dizocilpine (MK-801), a noncompetitive NMDA receptor antagonist, on TNBS (trinitrobenzene sulfoni...
The importance of the (pro)renin receptor (PRR) in the function of the central nervous system is increasingly evident because PRR seems to play a role in neuronal control of cardiovascular function. PRR expression is elevated in the nucleus of the solitary tract (NTS) of spontaneously hypertensive rats (SHR). In this study, we tested the hypothesis that altered activity of PRR in the NTS is lin...
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is a robust and powerful tool for studying biomacromolecules their interactions. However, quantitative detection of high-mass analytes (kDa to MDa range) remains challenging MALDI-MS. Herein, we successfully used commercially available purified proteins (?-galactosidase BSA) as internal standards MALDI-MS analysis achieved...
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