The migration of tumor cells of different degrees of invasivity is studied, on the basis of the traction forces exerted in time on soft substrates (Young modulus∼10 kPa). It is found that the outliers of the traction stresses can be an effective indicator to distinguish cancer cell lines of different invasiveness. Here, we test two different epithelial bladder cancer cell lines, one invasive (T...

The activation of stretch-activated calcium channels (SACs) in keratocytes can induce spatially coordinated increases in traction stress that promote protrusion at the cell front, while simultaneously inducing retraction at the rear. To investigate how this occurs, we correlated calcium-induced changes in traction stress with alterations in cell speed and shape. Cyclic changes in these paramete...

This paper describes the design, modeling, fabrication and characterization of a micromachined array of high-density 3-dimensional microposts (100×100) made of flexible material (silicone elastomers) for use to measure quantitatively the cellular traction force and contractile events in isolated vascular smooth muscle cells (VSMCs). The micropost array was fabricated with diameters ranged from ...

This study was designed to measure the efficacy of a nasal valve suspension technique and determine the adequate traction length without creation of nasofacial fullness in a cadaveric model. Seven fresh frozen cadaveric heads were evaluated. Minimal cross-sectional (MCA) areas were measured with a transient-signal acoustic rhinometer (Ecco Vision; Hood Instruments, Pembroke, MA) before and afte...

This paper reports a case of late vitreomacular traction in a young patient secondary to toxoplasma retinochoroiditis resolved by vitrectomy. A 17-year-old female with chronic inflammatory bowel disease developed severe vitreomacular traction 8 months after resolution of ocular toxoplasmosis with medical therapy. Best-corrected visual acuity, full ophthalmic slit-lamp examination, colour fundus...

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background: low back pain (lbp) is one of the most common musculoskeletal complications of today’s societies which, poses a big portion of health expenses and work absentees. lumbar disc herniation is claimed to be one of the several causes of lbp. conservative therapies like physiotherapy are found to be beneficial for treatment in such a kind of lbp. however, there is low evidence proving tra...

multiple sclerosis (ms) is an autoimmune inflammatory, demyelinating disease of human central nervous system. experimental autoimmune encephalomyelitis (eae) is the commonly used animal model of ms. calorie restriction has been found to reduce inflammation and autoimmune responses and promote neuroprotection. in this study we evaluated the effects of intermittent feeding protocol of the calorie...

objective to evaluate the efficacy and common side effects of intermittent clonazepam in febrile  seizures. materials & methods this study was an experimental trial designed to determine the efficacy of intermittent clonazepam in febrile seizures .thirty patients with an age range of 6 months to 5 years (60% male, 40% female) were studied. children with a history of psychomotor delay, abnormal ...