1 Introduction Recent studies of migraine-with-aura patients involving transmagnetic stimulation and visual stimulation have indicated enhanced excitability of the occipital cortex [1,2]. This hyperexcitability maybe the basis for Spreading Cortical Depression (SCD), which is thought to be the underlying mechanism of migraine-with-aura [3]. SCD and the resulting MEG signals are discussed in ref...

BACKGROUND Headaches are more frequent in Chronic Fatigue Syndrome (CFS) than healthy control (HC) subjects. The 2004 International Headache Society (IHS) criteria were used to define CFS headache phenotypes. METHODS Subjects in Cohort 1 (HC = 368; CFS = 203) completed questionnaires about many diverse symptoms by giving nominal (yes/no) answers. Cohort 2 (HC = 21; CFS = 67) had more focused ...

OBJECTIVE To identify the frequency of signs and symptoms of temporomandibular disorder (TMD) and its severity in individuals with headache. STUDY DESIGN 60 adults divided into three groups of 20 individuals: chronic daily headache (CDH), episodic headache (EH) and a control group without headache (WH). Headache diagnosis was performed according to the criteria of International Headache Socie...

BACKGROUND Existing criteria for the diagnosis of headache do not indicate which clinical features are most important to establish or exclude primary headache diagnoses. OBJECTIVE To determine the value of history taking in the evaluation of patients with primary headache syndromes. METHODS A MEDLINE search of English-language studies published since 1966 and a hand search of bibliographies...

OBJECTIVE To collect and analyse epidemiological data on childhood headache in the Hong Kong community. DESIGN Questionnaire study. SETTING Three primary schools, Hong Kong. PARTICIPANTS Two thousand, one hundred and twenty pupils from 2156 replied to the questionnaire survey. One hundred and twenty-four pupils who were identified to have suspected recurrent headache were invited to a fol...

Gary A. L’Europa MD, FASH  wHat CliniCal findings are Most useful for differentiating aMong tHe various types of HeadaCHes? When asked to comment on this topic I immediately thought of the advice that Seymour Diamond, founder of the Diamond Headache Center and the godfather of headache gave to his daughter Merl when she succeeded him as director, “Merl, it’s all migraine.” About 90% of all the...

OBJECTIVES Allergic rhinitis (AR) is an IgE mediated disease which is released by activation of mast cells and basophils, and often leads to sinus headache. Histamine which is the key mediator in the pathogenesis of AR, also plays an important role in the pathogenesis of migraine with nitric oxide (NO). Aim of our study was to investigate the frequency of migraine in patients with AR. METHODO...

BACKGROUND AND PURPOSE The etiology of headache in stroke is not known, and its relation to migraine and tension-type headache is unclear. The aim of our study was to investigate and classify headache appearing in stroke patients prospectively, using the new headache classification as determined by the Headache Classification Committee of the International Headache Society (1988). METHODS Two...

BACKGROUND Prophylactic treatment is an important but under-utilised option for the management of migraine. Patients and physicians appear to have reservations about initiating this treatment option. This paper explores the opinions, motives and expectations of patients regarding prophylactic migraine therapy. METHODS A qualitative focus group study in general practice in the Netherlands with...