BACKGROUND Vitamin K antagonist (VKA) therapy is safer and more effective when patients have a high time within the therapeutic range and low international normalised ratio variability. The SAMe-TT2R2 score aims to identify those at risk for poor VKA control. OBJECTIVES To evaluate the predictive value and clinical usefulness of the SAMe-TT2R2 score to identify those at risk for poor VKA cont...

The effect of noise variations on two of the short period seismic discriminants, spectral ratio and log-likelihood ratio is studied. The mean square errors of two different estimators of these two discriminants are evaluated and some theoretical and experimental results for two seismic signals in seismic noise are presented. Accepted for the Air Force Joseph R. Waterman, Lt. Col., USAF Chief, L...

OBJECTIVE To describe the magnitude and characteristics of crashes and drivers involved in head-on crashes on two-way interurban roads in Spain between 2007 and 2012, and to identify the factors associated with the likelihood of head-on crashes on these roads compared with other types of crash. METHODS A cross-sectional study was conducted using the National Crash Register. The dependent vari...

ii c 2013 Yi Liu ALL RIGHTS RESERVED iii ABSTRACT YI LIU. Generalized Quasi-Likelihood Ratio Statistics for Multivariate Time-varying Coefficient Regression Models. (Under the direction of DR. JIANCHENG JIANG) Generalized likelihood ratio statistics have been a generally applicable method for testing nonparametric hypotheses about nonparametric functions.It has been widely used in many research...

An all-optical 1×2 high contrast ratio (CR) switch based on the symmetric Mach-Zehnder (SMZ) interferometers is presented. Simulation results show a remarkable improvement of the inter-output CR (~25 dB) between the two outputs compared with an existing SMZ switch. It is shown that the proposed switch offers high values of inter-output CR (> 32dB) over a wide range of input powers using appropr...

BACKGROUND The objectives of this study were to determine rates of prenatal care utilization in Winnipeg, Manitoba, Canada from 1991 to 2000; to compare two indices of prenatal care utilization in identifying the proportion of the population receiving inadequate prenatal care; to determine the association between inadequate prenatal care and adverse pregnancy outcomes (preterm birth, low birth ...