1 of 2 DESCRIPTION A 78-year-old female presented with severe anaemia and melena. She had a history of impending intestinal obstruction of unknown cause 2 months before admission. An upper gastrointestinal (GI) series confi rmed the diagnosis of severe paraesophageal hiatus hernia, demonstrating the stomach and duodenum above the diaphragm ( fi gure 1A ), but no bleeding nor obstruction was fou...

NSAIDuse is limited due to the drugs' toxicity to the gastrointestinal mucosa, an action incompletely understood. Lower gut injury induced byNSAIDs is dependent on bile secretion and is reported to increase the growth of a number of bacterial species, including an enterococcal species,Enterococcus faecalis This study examined the relationships between indomethacin (INDO)-induced intestinal inju...

OBJECTIVES To study the effect of Nissen fundoplication and gastrostomy in severely neurologically impaired children. DESIGN Prospective observational study. SETTING Developmental Disabilities Unit of a regional medical centre in Hong Kong. PATIENTS Children with severe neurological impairment and gastroesophageal reflux who were institutionalised between 1999 and 2004 inclusive. MAIN O...

BACKGROUND AND AIMS To compare the performance of 3D magnetic resonance imaging (MRI) in conjunction with an intravascular contrast agent with that of scintigraphy, with respect to detection and localisation of gastrointestinal haemorrhage in vivo in pigs. METHODS Intraluminal bleeding sites were surgically created in the small bowel and colon of six pigs. The animals underwent scintigraphy w...

Obscure gastrointestinal bleeding is an important dilemma. Brunner's gland hamartoma is an extremely rare tumor generally localized in the duodenal bulb. We present a 34-year-old woman who had suffered from several episodes of melena for the past three years. Endoscopic examinations were normal. Computed tomography showed a large target lesion over the right abdomen and an image representing in...

We have reported good control of atypical genital bleeding when using a cyclic administration of dienogest (repeated 4-week cycles, each consisting of the administration of 2 mg/day of dienogest for 3 weeks, followed by 1 week of drug withdrawal) in patients with endometriosis. Herein, we report the effectiveness of the long-term cyclic administration (22 months) of dienogest in a case of patho...