Many physiologic functions fluctuate with time and the wave forms vary in complexity. Simple waves, such as the peripheral pulse, present no serious problem in analysis. When, however, the wave form is complex in appearance, existing analytic methods do not yield precise information. The general similarity between complex physiologic wave patterns and communication signals, such as sound waves,...

A 44-year-old woman is described with an endocrine tumour arising in the kidney. There were associated abnormalities of small intestinal morphology, motility, and absorptive function. These abnormalities reversed on removal of the tumour. Detailed studies showed that the tumour contained, and was secreting, glucagon. It is postulated that the intestinal abnormalities may have resulted from gluc...

We evaluated the effects of varying blood glucose concentration within the normal postprandial range and its interaction with small intestinal nutrients on antropyloric motility and appetite. Eight healthy males (19-40 yr) underwent paired studies, with a blood glucose level of 5 or 8 mmol/l. Manometry and visual analog scales were used to assess motility and appetite, during fasting and intrad...

BACKGROUND Near-infrared spectroscopy (NIRS) has the potential to continuously and noninvasively monitor intestinal function. This technology may be valuable because among neonates, intestinal maturity is highly variable and difficult to assess based solely on clinical signs. The aim of this study was to determine if there is an association between NIRS-based StO2 measurements and peristaltic a...

Background: Gastro-intestinal anastomosis is mostly performed to correct the gastro-intestinal surgical disorders like obstruction, abdominal trauma, perforated bowel, intussusception and intestinal neoplasia etc. In early periods conventional was followed which evolved into a seromuscular pattern of suture technique in recent years. Stapled have higher tensile strength than sutured anastomosis...

PURPOSE This study aimed to examine extended postoperative ileus and its risk factors in patients who have undergone abdominal surgery, and discuss the techniques of prevention and management thereof the light of related risk factors connected with our study. METHODS This prospective study involved 103 patients who had undergone abdominal surgery. The effects of age, gender, diagnosis, surgic...

Recently HUKUHARA, KOTANI and SATO7) found that morphine always exerted an excitatory action on the motility of dog jejunal Thiry-loop, literature concerned being reviewed there. They drew a conclusion that morphine acted as an excitant to the intestinal muscle itself, since it could raise the intestinal motility after atropine as well as hexamethonium had been administered and on the other han...

OBJECTIVE Dynamic imaging of small intestinal motility is an increasingly common research method to examine bowel physiology in health and disease. However, limited data exists to guide imaging protocols with respect to quantitative analysis. The purpose of this study is to define the required temporal resolution and scan duration in dynamic MRI for small bowel motility assessment. METHODS 6 ...

Antisecretory drugs such as histamine H₂-receptor antagonists and proton pump inhibitors are commonly used for the treatment of upper gastrointestinal mucosal lesions induced by nonsteroidal anti-inflammatory drugs (NSAIDs). However, it has recently been reported that these drugs exacerbate NSAID-induced small intestinal lesions in rats. Unfortunately, there are few effective agents for the tre...

The intestinal glucagon-like peptides GLP-1 and GLP-2 inhibit intestinal motility, whereas GLP-2 also stimulates growth of the intestinal mucosa. However, the mechanisms of action of these peptides in the intestine remain poorly characterized. To determine the role of the enteric nervous system in the actions of GLP-1 and GLP-2 on the intestine, the glial cell line-derived neurotropic factor fa...