The aim of this study was to estimate the time elapsed between the birth and the occurrence of catch-up growth in the first 12 months of life, in groups of infants born with low birth weight (less than or equal to 2500g). Postnatal catch-up growth had occurred in 100 cases (60 boys and 40 girls). There were no statistical differences between the sexes in the frequency of growth compensation and...

PURPOSE Heavy maternal drinking during pregnancy causes fetal alcohol syndrome, but whether more moderate alcohol consumption is associated with such adverse pregnancy outcomes as intrauterine growth retardation (IUGR) remains controversial. METHODS Using data from a case-control study, we examined the association between maternal alcohol consumption and risk for IUGR among 701 case and 336 c...

The joint associations of maternal cigarette smoking and social class on perinatal outcome were studied in the 1970 British birth cohort (British Births). Whereas smoking was much more frequent among women in social classes III, IV, and V, there was little difference in the birthweight decrement associated with smoking across class. Perinatal mortality, however, was increased only among smokers...

We report an infant with pre- and postnatal microcephaly and growth retardation, a distinctive face, and developmental delay. The initial diagnosis was of Seckel syndrome. He became pancytopenic at 16 months and died soon after. His bone marrow was of normal cellularity but had a small lymphocyte infiltration. Increased spontaneous chromosome breakage was seen in blood and fibroblasts. Mitomyci...

Cryptorchidism and hypospadias share possible risk factors, such as intrauterine growth retardation. According to the data collected by the International Clearinghouse for Birth Defects Monitoring Systems (ICBDMS), apparently increasing trends in the incidence of hypospadias were found in Sweden during the 1960s, and in Norway, Denmark, England and Hungary during the 1970s. In Norway and Denmar...

OBJECTIVE To study the role of hyperhomocysteinemia in patients with intrauterine growth retardation. METHOD 76 patients with intrauterine growth retardation were studied and compared with 50 controls which included pregnant patients without any pregnancy complications. Fasting Plasma homocysteine levels were measured and statistical analysis using tests of significance and logistic regressio...

An estimation of the baseline value of birth weight depending on gestational age is helpful for reducing morbidity and mortality following the early diagnosis and treatment of intrauterine growth retardation. In Korea, there are established baseline values for singletons and twins. But no definite criteria exist for triplets yet. Given the above background, we obtained the baseline value of bir...

The proband, a VA year old female child, was the first issue of a healthy couple (Fig. 1). The second issue which is a male child, is absolutely normal. The age of the mother and father was 30 and 35 years, respectively. The marriage was a non-consanguineous one. A detailed pedigree analysis revealed no chromosomal or genetic abnormality in the family. There was no previous history of miscarria...

Arend F Bos* MD PhD, Neonatologist, Department of Pediatrics, Beatrix Children’s Hospital, University Hospital, Groningen, The Netherlands; Christa Einspieler PhD, Associate Professor of Physiology, Department of Physiology, Karl Franzens University; Heinz F R Prechtl DM DPhil FRCOG (Hon), Professor Emeritus of Developmental Neurology, Department of Physiology, Karl Franzens University, Graz, A...

BACKGROUND/AIM Intrauterine growth retardation (IUGR) is a pathological condition of pregnancy characterised by birth weight below the 10th centile. A number of fetal, placental and maternal causes can lead to IUGR; although, in most cases no specific causes can be identified. The aim of this study was to determine the part of chromosomal abnormalities in IUGR etiology. METHODS Fetal blood ka...