Controlled drug delivery occurs when a polymer, whether natural or synthetic, is judiciously combined with a drug or other active agent in such a way that the active agent is released from the material in a predesigned manner. The release of the active agent may be constant over a long period, it may be cyclic over a long period, or it may be triggered by the environment or other external event...

The effect of dietary phytase and the prebiotic inulin on apparent mineral digestibility, bone mineralization, and tissue mineral contents was evaluated in weanling and growing pigs. In Exp. 1, inulin and phytase were incorporated in a 2 × 3 factorial arrangement of treatments with 8 replicate pens per treatment in a randomized complete block design. There were 2 levels of phytase [0 and 1000 p...

BACKGROUND Rats fed a high-fat and high-sucrose (HF) diet develop hepatic steatosis and hyperlipidemia. There are several reports that a change in nutritional status affects hepatic levels of drug-metabolizing enzymes. Synthetic inulin is a dietary component that completely evades glucide digestion. Supplementing a HF diet with inulin ameliorates hypertriglycemia and hepatic steatosis, but not ...

The effect of adding inulin to balanced diets for tropical gar (Atractosteus tropicus) larvae on growth, survival, digestive enzyme activity, and antioxidant activity was evaluated. were supplemented with 0.5, 1.0, 1.5, 2.0, 2.5% in addition a control diet (0% inulin). A total 1800 A. tropicus distributed 18 tanks used; the fed five times day (8:00, 11:00, 13:00, 15:00, 18:00) Artemia nauplii f...

Glycation between proteins and sugars via the Maillard reaction has been shown to improve heat stability of proteins. In this study, inulin, a healthy dietary fiber, was glycated with whey protein isolate (WPI), effects conditions were investigated. Conjugates prepared by freeze-drying mixed WPI inulin solutions at 1:1 6:1 WPI-to-inulin weight ratios followed dry heating 70, 75, or 80 °C for 12...

1. A serial study of renal clearance of urate and inulin was made in thirteen normal women in early, mid and late pregnancy and 6-15 weeks after delivery. 2. The mean serum urate concentration was low in early and mid pregnancy but rose in late pregnancy towards the control value. 3. Clearances of urate and inulin were consistently elevated throughout pregnancy to about 150% of the post-partum ...

The objective of this experiment was to investigate the potential influence of inulin on the establishment of new and patent infections of Trichuris suis in growing pigs. Two experimental diets were formulated based on barley flour with either added insoluble fibre from oat husk (Diet 1) or a pure inulin (16%) supplementation (Diet 2). Twenty-eight 10-week-old pigs were divided randomly into 4 ...

Key Message: The loss of mini-exon 2 in the 1-FEH IIb glycosyl-hydrolase results in a putative non-functional allele. This loss of function has a strong impact on the susceptibility to post-harvest inulin depolymerization. Significant variation of copy number was identified in its close paralog 1-FEH IIa, but no quantitative effect of copy number on carbohydrates-related phenotypes was detected...

Inulin, a linear beta fructan, is present in a variety of plants including chicory root and wheat. It exhibits prebiotic properties and has been shown to enhance mineral absorption and increase beneficial bacteria in the colon. The aim of the present study was to assess the effect of dietary inulin on the gene expression of selected intestinal Fe transporters and binding proteins. Anaemic pigle...

The effect of Bifidobacterium longum (4 x 10(8) viable cells/g diet) and a derivative of inulin ('Raftiline HP'; 5% w/w in diet) on colonic aberrant crypt foci (ACF) induced by the colon carcinogen azoxymethane (AOM) has been studied. The concentration of ammonia, a putative tumour promoter produced by bacterial degradation of protein and urea, and the activities of certain bacterial enzymes th...