There is great interest in the use of single-nucleotide polymorphisms (SNPs) and linkage disequilibrium (LD) analysis to localize human disease genes. The results suggest that the human genome, including the major histocompatibility complex (MHC), consists largely of 5- to 200-kb blocks of sequence fixity between which random recombination occurs. Direct determination of MHC haplotypes from fam...

There continue to be numerous breaches publicised pertaining to cyber security despite security practices being applied within industry for many years. This article is intended to be the first in a number of articles as research into cyber security assurance processes. This article is compiled based on current research related to cyber security assurance and the impact of the human element on i...

Tuberculosis (TB) is one of the most important occupational risks for healthcare workers (HCWs) in South Korea. Many policies regarding the control and prevention of TB in healthcare settings recommend that HCWs are tested for latent tuberculosis infection (LTBI) in addition to active TB. Moreover, the Korean Tuberculosis Prevention Act also recommends that HCWs receive regular testing for LTBI...

Subjective well-being (SWB) is a major topic of research across the social sciences. Twin and family studies have found that genetic factors may account for as much as 30-40% of the variance in SWB. Here, we study genetic contributions to SWB in a pooled sample of ~11,500 unrelated, comprehensively-genotyped Swedish and Dutch individuals. We apply a recently-developed method to estimate “common...

In several reports the authors have suggested occasional familial aggregation of syringomyelia and/or Chiari 1 malformation (CM1). Familial aggregation is one characteristic of traits that have an underlying genetic basis. The authors provide evidence for familial aggregation of CM1 and syringomyelia (CM1/S) in a large series of families, establishing that there may be a genetic component to CM...

the geometry of a collector is one of the important factors that can increase the incident radiation on the collector surface. in the present study, the incident radiation for a stationary collector with cone geometry, i.e. a conical collector, is theoretically and experimentally investigated. this type of collector is always stable and does not need a fixture to install. moreover, it has a sym...

objective(s): in this work, electrospun nanofibers were explored as drug delivery vehicles using tetracycline as a model drug.  nanocomposite fibers including chitosan (cs)/poly (ethylene oxide) (peo) and antibiotic were successfully prepared using electrospinning. cs blended with peo considering a weight ratio of (90/10), and then, nanofibrous samples were successfully electrospun from their a...

tissue engineering is defined as the designing and engineering of structures to rebuild and repair a body damaged tissue. scaffolding poly hydroxy butyrate valraty (phbv) has shown good biocompatibility and biodegradable properties. nanofibers have improved the performance of biomaterials, and could be considered effective. one of the important methods for designing nanofiber scaffold is the el...

IMPORTANCE In the past decade, significant progress in genomic medicine and technologic developments has revolutionized our approach to common complex disorders in many areas of medicine, including ophthalmology. A disorder that still needs major genetic progress is diabetic retinopathy (DR), one of the leading causes of blindness in adults. OBJECTIVE To perform a literature review, present t...