Undesirable taste is one of several important formulation problems that are encountered with certain drugs. The problem of bitter and obnoxious taste of is a challenge to the pharmacist in the present scenario. Several oral pharmaceuticals and bulking agents have unpleasant, bitter-tasting components. The desire of improved palatability in these products has prompted the development of numerous...

The aim of the present study was to determine the ability of a dentifrice containing a mixture of ion-exchange resins (named NMTD), which supplies calcium, fluoride, phosphate, and zinc ions, to promote remineralization and/or inhibit demineralization of dental human enamel in a pH cycling model in vitro. A fluoride toothpaste was used as the control. The enamel specimens were tested for microh...

Heterogeneous proton exchange membranes (PEM) are synthesized using the dry phase inversion technique. The casting solutions are prepared by dispersing a finely ground cation exchange resin particle in N,N-dimethylacetamide (DMAc) solution of polyvinyl-chloride (PVC). Results show that ion exchange capacity is increased with the addition of 1 %-wt nanosilica (from 0.14 to 0.27 meq/g) while it i...

Creatine kinase isoenzyme MB catalytic activities in human serum, determined by ACA ion exchange chromatography and immunoinhibition, differ significantly, the correlation coefficient being 0.88. The reasons for this variation are interference of antibodies with the creatine kinase B subunit in the immunoinhibition assay, nonreproducible elution of creatine kinase isoenzyme MB from the ion exch...

HE INTRODUCTION OF the carboxylic acid cation exchange Amberlite XE-96 (or IRC-50) Azure A resin’ as the medium for hydrogen ion exchange in place of the quininium exchange resin has simplified greatly the determination of gastric acidity without intubation (1). Solvent extraction and fluorimetry are no longer required. The amount of blue dye excreted in the urine is readily measured by visual ...

lon-chromatography, a relatively new technique in a nal yti cal chemistry, has already shown great promise toward solving complex trace analysis problems, in particular the speciat ion and quantitation of allion~. It is especially attractive to the fi e ld of microanalysis. The method of sample preparation, however, is (Tucial in order to realize this capac it y. Existing microanalytical method...

Herein, we report on the fabrication of a device for removing cations of an anti-analyte ion contained in a sample and an eluent under an electric field. The space in which the electrode is set on both sides of the device is separated into three cells using anion and cation exchange membranes. Each of the cells is packed with either an anion or cation exchange resin. Cation removal is perfor...