Over the past few decades, molecularly imprinted polymers (MIPs) have become extremely attractive materials for biomimetic molecular recognition due to their excellent affinity and specificity, combined with robustness, easy engineering, competitive costs. MIPs are synthetic antibody mimics obtained by synthesis of 3D polymer networks around template molecules, thus generating specific binding ...

Molecular imprinting is a technique for making a selective binding site for a specific chemical. The technique involves building a polymeric scaffold of molecular complements containing the target molecule. Subsequent removal of the target leaves a cavity with a structural "memory" of the target. Molecularly imprinted polymers (MIPs) can be employed as selective adsorbents of specific molecules...

Inherently conducting polymers have been used in several applications for flexible electronics, for example in organic thin film transistors (OTFT), organic light emitting diodes (OLED), organic photovoltaic cells and electrochromic devices [1-3]. Nanoimprinting may offer a high throughput method to produce low cost devices [4] also when functional polymers such as conducting polymers are used....

Molecular imprinting is a technique used to synthesize polymers that display selective recognition for a given molecule of interest. In this study, the role of hydrogel electrostatic charge density on the recognition and selectivity properties of protein-imprinted hydrogels was explored, and the effect of variations of the template extraction protocol on the MIP recognition properties were also...

A glass slide covered with bacteria is pressed into another glass slide coated with partially cured polydimethylsiloxane (PDMS). The PDMS is hardened and the cells are removed to create a textured surface whose indentations preferentially capture the same type of bacteria when a mixture of bacteria is flowed over it. Overcoating the cell-imprinted PDMS with methylsilane groups causes the result...

The sample treatment/preparation steps involve any operation and manipulation of the samples prior to instrumental determination of the target compounds [1−3]. This is a critical step in the analytical process because the concentration of target analytes in the samples is frequently too low for quantification. Thus, the first step of the preparation protocol involves the exhaustive extraction/c...

Artificial receptors have been in use for several decades as sensor elements, in affinity separation, and as models for investigation of molecular recognition . Although there have been numerous publications on the use of molecular modeling in characterization of their affinity and selectivity, very few attempts have been made on the application of molecular modeling in computational design of ...

The origin of the improved performance Molecular Imprinted Polymers (MIPs) prepared by Nitroxide-Mediated Radical Deactivation Reversible Polymerization (NMRP) and conventional Free (FRP) was investigated through a detailed interpretation adsorption onto imprinted- non-imprinted materials. MIPs designed for 3,5-dichlorohydroxyacetophenone (DCHA) were copolymers methacrylic acid styrene cross-li...

A new type of insulin delivery system capable of better self-regulating the release of insulin was reported in this study. This insulin delivery system was made of a low crosslinked insulin-imprinted hydrogel that exhibited pH-dependent interpolymer interactions between poly(methacrylic acid) (PMAA) and poly(ethylene glycol) (PEG). At acidic conditions (such as pH 3.5), this delivery system res...

In recent years, molecularly-imprinted polymers (MIPs) have attracted the attention of several researchers due to their capability for molecular recognition, easiness of preparation, stability and cost-effective production. By taking advantage of these facts, Hg(II) imprinted and non-imprinted copolymers were prepared by polymerizing mercury nitrate stock solution (or without it) with methacryl...