background: hepatitis a virus (hav) is a single strand and non-enveloped rna virus. it is usually transmitted by the fe­cal-oral and the blood transfusion routes and causes the hepatitis a disease. clinically, the hepatitis a is usually mild, par­ticularly in children, in whom it is frequently subclinical. the disease is more serious and prolonged in adults. the objective of this study was to f...

no abstract

background: the development of anti-red blood cell alloantibodies remains a major problem in transfusion of blood in thalassemia major patients. also, autoantibodies can result in clinical hemolysis and difficulty in cross-matching blood. we studied the frequency of red blood cell alloimmunization and autoimmunization among thalassemia patients who received regular transfusions in ilam province...

Background: Pseudocholinesterase (PChE) polymorphism has been a subject of several pharmacogenetic studies worldwide. The patients with atypical homozygous genotype do not only have reduced serum cholinesterase activities but also their elimination rate for some pharmacologically potent drugs decrease drastically. This study was designed to evaluate the PChE polymorphism in Mazandaran province ...

Background & Objective: Bacterial, contamination of blood components are a significant risk for transfusion reactions. Inherently, platelet concentrates (PCs) are vulnerable to bacterial contamination, due to the storage condition of processed PCs at room temperature, which provide very suitable conditions for the proliferation of microorganisms....

BACKGROUND Unnecessary perioperative transfusions are likely to be related to increased morbidity and additional costs in cardiac surgery. OBJECTIVES The aim of this study was to evaluate the blood transfusion practice during and after adult cardiac surgery in a referral university hospital in Iran. PATIENTS AND METHODS In a descriptive study, we collected data from 153 adult patients under...

Blood transfusion has a well-documented clinical significance in several medical scenarios for instance severe anemia, massive blood loss caused by trauma, and major surgeries. Nevertheless, been associated with post-transfusion complications, such as mismatch reactions, transfusion-transmitted infections (TTIs).

background: the most appropriate route of tranexamic acid administration is controversial. in the current study, we compared the efficacy of intravenous (iv) and topical intra-articular tranexamic acid in reducing blood loss and transfusion rate in patients who underwent primary total knee arthroplasty. methods: one hundred twenty 120 patients were scheduled to undergo primary total knee arthro...