نتایج جستجو برای: iridocorneal endothelial syndrome

تعداد نتایج: 746121  

2017
Karolina Krix-Jachym Tomasz Żarnowski Marek Rękas

Purpose The aim of this study was twofold: first, to evaluate the predisposing factors for occurrence of malignant glaucoma and second, to compare frequency of malignant glaucoma depending on the type of primary glaucoma surgery. Methods Retrospective analysis was performed in 1689 consecutive patients who underwent glaucoma surgery alone or combined with phacoemulsification. Data collected i...

2011
Richard McKeone Helena Vieira Kevin Gregory-Evans Cheryl Y. Gregory-Evans Paul Denny

Anterior segment dysgenesis (ASD) is characterised by an abnormal migration of neural crest cells or an aberrant differentiation of the mesenchymal cells during the formation of the eye's anterior segment. These abnormalities result in multiple tissue defects affecting the iris, cornea and drainage structures of the iridocorneal angle including the ciliary body, trabecular meshwork and Schlemm'...

2014
Carmen Lopez de la Fuente Ana Sanchez-Cano Francisco Segura Lorena Fuentes-Broto Isabel Pinilla

PURPOSE To assess the repeatability of the Galilei dual Scheimpflug analyzer (GDSA) in anterior segment examination. METHODS Fifty-two eyes from 52 healthy volunteers were prospectively and consecutively recruited. Anatomic, axial, refractive, and instantaneous parameters were measured with GDSA to provide a complete characterization of the anterior segment. Repeatability was assessed calcula...

2016
Shozaburo Yanamoto Jiro Fukae Yurie Fukiyama Shinsuke Fujioka Shinji Ouma Yoshio Tsuboi

BACKGROUND Remitting seronegative symmetrical synovitis with pitting edema syndrome is characterized by symmetrical synovitis with pitting edema in the dorsum of the hands or feet. Most cases of remitting seronegative symmetrical synovitis with pitting edema syndrome are idiopathic, but some are secondary to malignancy, autoimmune disease, or neurodegenerative disorders. Pleural and pericardial...

Journal: :European heart journal 2003
Meral Kayikcioglu Serdar Payzin Oguz Yavuzgil Hakan Kultursay Levent H Can Inan Soydan

AIMS The pathophysiological mechanism in cardiac syndrome-X (anginal chest pain, positive exercise test, and angiographically normal coronary arteries) has been suggested as an impairment in normal endothelial function of the coronary microvasculature, resulting in inadequate flow reserve. The aim of this study was to determine whether statins with proven beneficial effects on endothelium, have...

2011

Objective Increased nuchal translucency in the human fetus is associated with aneuploidy, structural malformations and several syndromes such as Noonan syndrome. In 60-70% of the Noonan syndrome cases, a gene mutation can be demonstrated. Previous research showed that aneuploid fetuses with increased nuchal translucency demonstrate an aberrant lymphatic endothelial diff erentiation. Methods Fet...

2015
Hui Guo Xinyi Wu Keli Cai Zhi Qiao

BACKGROUND To report the diagnostic features and management strategy of a rare case of Weill-Marchesani syndrome with advanced glaucoma and corneal endothelial dysfunction. CASE PRESENTATION A patient presented with advanced glaucoma with an intraocular pressure of 49 mmHg in the left eye, and subsequently received trabeculectomy to control the intraocular pressure. Surprisingly, slit lamp ex...

Journal: :Investigative ophthalmology & visual science 2009
Ramez I Haddadin Dong-Jin Oh Min Hyung Kang Theodoros Filippopoulos Meenakashi Gupta Lois Hart E Helene Sage Douglas J Rhee

PURPOSE SPARC is a matricellular protein that is highly expressed in remodeling tissues, including the trabecular meshwork and ciliary body. The hypothesis for the study was that SPARC contributes to the regulation of intraocular pressure (IOP). The IOPs of SPARC-null mice, their corresponding wild-type (WT), and heterozygous animals were compared. METHODS Diurnal and nocturnal IOPs of C57Bl/...

Journal: :Investigative ophthalmology & visual science 2008
Yu Zhou Oleg Grinchuk Stanislav I Tomarev

PURPOSE To developed a genetic mouse model of primary open-angle glaucoma induced by expression of mutated human myocilin in transgenic mice and to test whether expression of mutated human myocilin in the eye angle structures produces more significant damage to the eye than does mutated mouse myocilin. METHODS Recombineering in Escherichia coli was used to introduce the Tyr437His point mutati...

Journal: :Investigative ophthalmology & visual science 2010
Sinisa D Grozdanic Helga Kecova Matthew M Harper Wijitha Nilaweera Markus H Kuehn Randy H Kardon

PURPOSE To characterize functional and structural changes in a canine model of hereditary primary angle-closure glaucoma. METHODS Intraocular pressure (IOP) was evaluated with tonometry in a colony of glaucomatous dogs at 8, 15, 18, 20, and 30 months of age. Retinal function was evaluated using electroretinography (scotopic, photopic, and pattern). Examination of anterior segment structures w...

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