Groundwater, being a vital resource, needs to be developed with proper understanding about its occurrence in time and space. Unscientific sand mining is a dominant environmental issue in this humid tropical river basin namely Bharathapuzha river basin geographically on central part of Kerala state, southwest part of India. The sandy layers along the river course declines its water holding capac...

Insulin receptor substrate 1 (IRS-1), and its structural relative IRS-2, are both phosphorylated on tyrosine following treatment of cells with interleukin-4 (IL-4) and insulin. We have investigated whether both IRS-1 and IRS-2 are expressed in murine lymphohemopoietic cells. T and B lymphocytes and macrophages from primary cultures expressed only IRS-2, which became phosphorylated on tyrosine f...

Pictures are the most effective means of conveying information. A picture is worth a thousand words. Pictures concisely convey information about positions, sizes and interrelationships between objects. Human beings are good at deriving information from such images, because of our innate visual and mental abilities. About 75% of the information received by human is in pictorial form. The paper d...

Introduction Conclusions References Tables Figures Back Close Full Screen / Esc This discussion paper is/has been under review for the journal Earth System Dynamics (ESD). Please refer to the corresponding final paper in ESD if available. Abstract Introduction Conclusions References Tables Figures Back Close Full Screen / Esc Abstract The Kaziranga National Park is a forest-edged riverine grass...

ISSN 2277 – 503X | © 2012 Bonfring Abstract--The Remote sensing technology is measured or observed reflected energy to construct an image of the landscape beneath the platform passage in a discrete pixel format. The geometric and radiometric characteristics of remotely sensed image provide information about earth’s surface. In the present study, the primary data product obtained from IRS P6 sat...

To examine the impact of homozygous genetic disruption of IRS-1 (IRS-1-/-) or IRS-2 (IRS-2-/-) on basal and insulin stimulated carbohydrate and lipid metabolism in vivo we infused 18-h fasted mice (WT, IRS1-/and IRS2-/-) with [3-3H]glucose and [H5]glycerol and assessed rates of glucose and glycerol turnover under basal (0-90 min) and hyperinsulinemic-euglycemic clamp (90-210 min; 5 mM glucose a...

BACKGROUND Indoor residual spraying (IRS) for malaria prevention has traditionally been implemented in Ethiopia by the district health office with technical and operational inputs from regional, zonal, and central health offices. The United States President's Malaria Initiative (PMI) in collaboration with the Government of Ethiopia tested the effectiveness and efficiency of integrating IRS into...

The insulin receptor substrate (IRS) proteins are cytoplasmic adaptors that organize signaling complexes downstream of activated cell surface receptors. Here, we show that IRS-1 and IRS-2, despite significant homology, play critical yet distinct functions in breast cancer, and we identify specific signaling pathways that are influenced by IRS-1 using the polyoma virus middle-T (PyV-MT) transgen...

Insulin receptor substrate-2 (IRS-2) is phosphorylated on tyrosine by a number of cytokine receptors and is implicated in the activation of phosphatidylinositol 3'-kinase (PI3-kinase). Here, we demonstrate that induction of granulocytic differentiation of human promyeloid HL-60 cells leads to an increase in the amount of IRS-2 that is phosphorylated in response to insulin-like growth factor (IG...

Insulin receptor substrate 1 (IRS-1) gene polymorphisms have been identified in type 2 diabetic patients; however, it is unclear how such polymorphisms contribute to the development of diabetes. Here we introduced obesity in heterozygous IRS-1 knockout (IRS-1(+/-)) mice by gold-thioglucose (GTG) injection and studied the impact of reduced IRS-1 expression on obesity-linked insulin resistance. G...