نتایج جستجو برای: ischemia reperfusion injuries

تعداد نتایج: 209679  

Journal: :Actas urologicas espanolas 2008
R Alvarez-Vijande P Luque Gálvez A Alcaraz Asensio

INTRODUCTION AND GOALS Renal procurement after a period of heart st op demands a previous knowledge of ischemia-reperfusion injuries means. To study cell injury mechanisms an experimental study has been designed in pigs, with different rangres of warm ischemia (0-30-45 and 90 min). The main goal was to research on the basis of ischemic injury. MATERIAL AND METHODS Biochemical parameters (crea...

Journal: :iranian journal of basic medical sciences 0
vedat ugurel university of trakya, faculty of medicine, department of obstetrics and gynecology, 22030, balkan campus, edirne, turkey ahmet cagatay cicek university of trakya, faculty of medicine, department of histology and embryology, 22030, balkan campus, edirne, turkey mustafa cemek yildiz technical university, biochemistry division, department of bioengineering, faculty of chemical and metallurgical engineering, istanbul, turkey selim demirtas university of trakya, faculty of medicine, department of histology and embryology, 22030, balkan campus, edirne, turkey a tuba kocaman yildiz technical university, biochemistry division, department of bioengineering, faculty of chemical and metallurgical engineering, istanbul, turkey turan karaca university of trakya, faculty of medicine, department of histology and embryology, 22030, balkan campus, edirne, turkey

objective(s): to evaluate the protective effect of erdosteine, an antiapoptotic and antioxidant agent, on torsion–detorsion evoked histopathological changes in experimental ovarian ischemia-reperfusion (ir) injury. materials and methods: eighteen female wistar albino rats were used in control, ir, and ir+edosteine (ir-e) groups, (n=6 in each). the ir-e group received the erdosteine for seven da...

Journal: :trauma monthly 0

background renal ischemia reperfusion (ir) contributes to the development of acute renal failure (arf). oxygen free radicals are considered principal components involved in the pathophysiological tissue alterations observed during renal ir. objective in this study, we compared the effects of melatonin (mel) and erythropoietin (epo), which are known antioxidant and anti-inflammatory agents, in i...

Journal: :acta medica iranica 0
r. rabani h. r. sadeghipour-roodsari h. sepehri a. a. hassanzadeh-salmasi a. r. dehpour

anandamide is an endogenous ligand for cannabinoid receptors and has endothelial protective effect against ischemic preconditioning. the purpose of this study was to investigate the effects of cannabinoids on reperfusion injury due to testicular torsion-detorsion (t/d). a total of 36 adult male sprague-dawley rats were divided into 6 groups. testicular ischemia was achieved by twisting the righ...

Journal: :iranian journal of basic medical sciences 0
javad raouf sarshoori department of anatomy, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran mohammad hossien asadi department of anatomy, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran mohammad taghi mohammadi department of physiology and biophysics, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran

objective(s): some histopathological alterations take place in the ischemic regions following brain ischemia. recent studies have demonstrated some neuroprotective roles of crocin in different models of experimental cerebral ischemia. here, we investigated the probable neuroprotective effects of crocin on the brain infarction and histopathological changes after transient model of focal cerebral...

2011
Hui Ding Cai-Zhen Yan Honglian Shi Ya-Shuo Zhao Shi-Yang Chang Peng Yu Wen-Shuang Wu Chen-Yang Zhao Yan-Zhong Chang Xiang-Lin Duan

Oxidative stress plays an important role in neuronal injuries caused by cerebral ischemia. It is well established that free iron increases significantly during ischemia and is responsible for oxidative damage in the brain. However, the mechanism of this ischemia-induced increase in iron is not completely understood. In this report, the middle cerebral artery occlusion (MCAO) rat model was perfo...

Journal: :physiology and pharmacology 0
abedin vakili department of physiology, faculty of medicine, semnan university of medical sciences, semnan, iran somaye mojarrad department of physiology, faculty of medicine, semnan university of medical sciences, semnan, iran

pervious studies have shown that pentoxifylline (ptx) has beneficial effects in reduction of stroke and brain trauma injuries in experimental animals. however, there is very little and controversial information about the effect of ptx on brain edema in cerebral ischemia. therefore, the aim of this study was to determine the effects of different doses of ptx on brain edema and neurological motor...

2013
Dimitrios Papadopoulos Thomas Siempis Eleni Theodorakou Georgios Tsoulfas

CONTEXT Ischemia-reperfusion injury is a fascinating topic which has drawn a lot of interest in the last several years. Hepatic ischemia reperfusion injury may occur in a variety of clinical situations. These include transplantation, liver resection, trauma, and vascular surgery. EVIDENCE ACQUISITION The purpose of this review was to outline the molecular mechanisms underlying hepatic I/R inj...

Journal: :Journal of immunology 2006
Rodney K Chan Shahrul I Ibrahim Kazue Takahashi Edwin Kwon Michael McCormack Alan Ezekowitz Michael C Carroll Francis D Moore William G Austen

Complement is an important mediator of the injuries observed after skeletal muscle ischemia and subsequent reperfusion. Although the classical pathway had been assumed to be the major pathway of activation leading to injury, the mannose-binding lectin (MBL) pathway might also play a contributing role. In this study, we found that MBL-deficient mice had significant protection after skeletal musc...

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