نتایج جستجو برای: ivt mrna
تعداد نتایج: 153383 فیلتر نتایج به سال:
effect of intravitreal triamcinolone (ivt) injection on visual acuity in patients with ischemic crvo
purpose: to determine the effect of intravitreal triamcinolone (ivt) injection on visual acuity in patients with ischemic central retinal occlusion (crvo). methods: this randomized clinical trial was performed on patients with ischemic crvo referred to the retina clinic at feiz hospital in 2007-2008. inclusion criteria were: duration of crvo less than one month, normal iop, no sign of diabetic ...
PURPOSE Gene transduction using adenoviral vectors is an important research tool. To assess and optimize this technique for glaucoma research, we characterized green fluorescent protein (GFP) expression in the mouse eye after intraocular injection of adenoviral vector encoding GFP (Ad5.CMV-GFP) and evaluated the effect of anti-CD40L antibody administration on GFP expression. METHODS Mice were...
Rivaroxaban, a novel direct factor Xa inhibitor with consistent anticoagulant properties, was found to be safer and equally effective as warfarin in the prevention of embolic stroke in patients with nonvalvular atrial fibrillation [1, 2] . Effective anticoagulation predisposes to bleeding and represents a contraindication for intravenous thrombolysis (IVT) with recombinant tissue plasminogen ac...
Intravitreal (IVT) injections are the current method for retinal drug delivery and have been widely used in humans, although it is well known that IVT often cause an increase intraocular pressure (IOP) closely relates to injection volume. Because of anatomical physiological similarities monkey human eye, cynomolgus monkeys preclinical studies on new treatments using large molecules or gene ther...
BACKGROUND AND PURPOSE Reports on the safety and efficacy of intraventricularly administered (IVT) colistin for the treatment of Acinetobacter baumannii ventriculomeningitis in adults are limited and no comparative studies of IVT colistin versus intravenous (IV) therapy alone have been published. This study compared outcomes of patients with postneurosurgical ventriculomeningitis caused by exte...
Background: Sex differences in treatment response to intravenous thrombolysis (IVT) are poorly characterized. We compared sex-disaggregated outcomes patients receiving IVT for acute ischemic stroke the Alteplase Tenecteplase (AcT) trial, a Canadian multicentre, randomised trial. Methods: In this post-hoc analysis, primary outcome was excellent functional (modified Rankin Score [mRS] 0-1) at 90 ...
BACKGROUND AND PURPOSE Decreasing the time delay for thrombolysis, including intravenous thrombolysis (IVT) with tissue plasminogen activator and intra-arterial thrombectomy (IAT), is critical for decreasing the morbidity and mortality of patients experiencing acute stroke. We aimed to decrease the in-hospital delay for both IVT and IAT through a multidisciplinary approach that is feasible 24 h...
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