Bisphosphonates are nonmetabolizable analogs of pyrophosphates. They have a high selectivity to bone remodeling sites, become retained and recycled, providing a long duration of continual effect after discontinuation. Bisphosphonates have been registered for postmenopausal osteoporosis for 20 years. Four bisphosphonates are currently registered for postmenopausal osteoporosis – alendronate, ris...

Aim: The zygomatic bone is the key component of the structural facial aesthetics as it constitutes the prominence of the cheek bone. Also, the most frequent clinical findings in zygomatic arch fracture includes limitation of jaw movement and flattening of cheek. So it is necessary to elevate the arch precisely. Therefore, a prospective study was conducted toevaluate adequacy for reduction of zy...

OBJECTIVES Transpositioning of the inferior alveolar nerve to prevent injury in lower jaw has been advocated for orthognathic, pre-prosthetic and for implant placement procedures. However, the concept of infra-orbital nerve repositioning in cases of mid-face fractures remains unexplored. The infraorbital nerve may be involved in trauma to the zygomatic complex which often results in sensory dis...

PURPOSE To describe the rationale and methods for a prospective, open-cohort study assessing the long-term safety of Prolia(®) for treatment of postmenopausal osteoporosis (PMO) in postmarketing settings. METHODS Data will be derived from United States Medicare, United Healthcare, and Nordic (Denmark, Sweden, Norway) national registries. Observation will begin on the date of first Prolia(®) r...

conclusions we reported a rare case of large residual cyst. dental practitioners should consider this lesion in the differential diagnosis of radiolucent lesions of the jaw bone. case presentation a 59-year-old iranian man complaining of a dull pain in his left side of the mandible after falling down one month ago was referred to the department of oral and maxillofacial pathology, hamadan unive...

The aim of this study was to evaluate the potential advantages and clinical results of a modified minimally invasive ilioinguinal approach for the treatment of acetabular or pelvic fractures to the results obtained using a standard ilioinguinal approach. Forty-six patients who were diagnosed as having anterior column acetabular fractures or anterior pelvic ring fractures underwent open reductio...

Randomized controlled trials have demonstrated the efficacy of bisphosphonates (BP) in improving BMD and reducing fracture risk. Various safety issues that were not noted in clinical trials have, however, now emerged with post-marketing surveillance and increasing clinical experience. The risk of atypical femoral fracture could increase with long-term use of BP, although absolute risk is very s...

OBJECTIVES This in vitro study tested the influence of diverse stress simulation parameters on the fracture strength of all-ceramic three-unit fixed partial dentures (FPDs). METHODS All-ceramic FPDs made of Empress 2 (Ivoclar-Vivadent, FL) were exposed to thermal cycling and mechanical loading (TCML) with varying loading parameters such as chewing force (amount, frequency), thermal loading, l...