Non-homologous end-joining (NHEJ) is a critical error-prone pathway of double strand break repair. We recently showed that tyrosyl DNA phosphodiesterase 1 (Tdp1) regulates the accuracy of NHEJ repair junction formation in yeast. We assessed the role of other enzymes in the accuracy of junction formation using a plasmid repair assay. We found that exonuclease 1 (Exo1) is important in assuring ac...

Ready-made building components and joining systems are generally unfit for existing building structures with irregular shapes. Therefore, unplanned and immediate manual work is dominantly practiced as measuring and manufacturing of the customized joining system is not supported. In this respect, by obtaining 3-D shapes of the existing building components and using them for the customization of ...

Joints in product design are common because of the limitations of component geometric configurations and material properties, and the requirements of inspection, accessibility, repair, and portability. Collaborative product design is emerging as a viable alternative to the traditional design process. The collaborative assembly design (AsD) methodologies are needed for distributed product develo...

Joining technologies are very important aspects of production process in the automotive. Especially regarding use newly developed types materials (e.g. ultra high-strength steels or aluminium alloys), addition to welding technology, e.g. riveting adhesive bonding used. Submitted article evaluates effect force on final quality riveted joint when joining alloy EN AW-6016 (thickness 2 mm). The act...