Blood Transfus 2007; 5: 50-57 © SIMTI Servizi Srl The Rhesus factor is clinically the most important protein-based blood group system. With 49 antigens so far described, it is the largest of all 29 blood group systems. The unusually large number of Rhesus antigens is attributable to its complex genetic basis. The antigens are located on two Rhesus proteins RhD and RhCE and are produced by diffe...

Muscle pathology in McLeod syndrome is usually mild; patchy necrotic or regenerating fibres, occasional internal nuclei, and the absence of an inflammatory cell infiltrate are the usual findings. We report on a 29 year old man presenting with chronic fatiguability and excessive sweating in whom an open quadriceps muscle biopsy demonstrated grouped necrotic fibres accompanied by striking patchy ...

There are two models to account for the large population of GPI-negative cells and the occasional demonstration of oligoclonality in paroxysmal nocturnal hemoglobinuria (PNH): i) immune escape; and ii) hypermutability. In support of immune escape, in PNH, marrow failure is common and is associated with HLA-DR alleles and oligoclonal T-cell expansions. Conversely, in support of hypermutability, ...

Lubinski, D., Benbow, C. P., & Kell, H. J. (2014). Life paths and accomplishments of mathematically precocious males and females four decades later. Psychological Science, 25, 2217-2232. (Original DOI: 10.1177/0956797614551371).

The Kell Calculus is a family of process calculi intended as a basis for studying distributed component-based programming. This paper presents an abstract machine for an instance of this calculus, a proof of its correctness, and a prototype OCaml implementation. The main originality of our abstract machine is that it does not mandate a particular physical configuration (e.g. mapping of localiti...