Hundreds of clinical trials are currently investigating the potential for mesenchymal stem cells (MSC) to treat human disease, including kidney disease. There is tremendous excitement over the therapeutic potential of this form of stem cell therapy and an improving understanding of how MSC act. This review will summarize our current knowledge concerning the mechanisms by which MSC accelerate ki...

background: diagnosis of kidney scar could prevent vesico urethral reflax and its complications such as hypertension and renal failure. this study was conducted to determine average kidney length and volume in infants by sonography to accurate diagnosis of scars. methods: this study was conducted on infants with the history of uti who referred to imam reza hospital, kermanshah iran, for dmsa sc...

Drug induced kidney injury is a frequent adverse event which contributes to morbidity and increased healthcare utilization. Our current knowledge of drug induced kidney disease is limited due to varying definitions of kidney injury, incomplete assessment of concurrent risk factors and lack of long term outcome reporting. Electronic surveillance presents a powerful tool to identify susceptible p...

How to cite this article: Agaba EI, Agaba PA, Dankyau M, et al. Specialist physician knowledge of chronic kidney disease: A comparison of internists and family physicians in West Africa. Afr J Prm Health Care Fam Med. 2012;4(1), Art. #319, 7 pages. http://dx.doi.org/10.4102/ phcfm.v4i1.319 Background: Postgraduate training is aimed at equipping the trainee with the necessary skills to practise ...

The mammalian kidney is a vital organ with considerable cellular complexity and functional diversity. Kidney development is notable for requiring distinct but coincident tubulogenic processes involving reciprocal inductive signals between mesenchymal and epithelial progenitor compartments. Key molecular pathways mediating these interactions have been identified. Further, advances in the analysi...

BACKGROUND Many patients with chronic kidney disease (CKD) have insufficient knowledge about CKD, which is associated with poorer health outcomes. Effective patient-provider communication can improve CKD patients' knowledge, thereby augmenting their participation in self-care practices. However, barriers to addressing CKD patients' information needs have not been previously characterized. MET...

BK polyomavirus (BKV) mainly causes infection in uroepithelial and renal tubular epithelial cells of either immunocompetent or immunocompromised hosts. Despite asymptomatic mild clinical features hosts with infection, serious complications are frequently found patients, especially patients kidney transplantation. Accordingly, BKV-associated nephropathy (BKVN) demonstrates a wide range manifesta...

PURPOSE The purpose of this review is to provide a summary of the rationale for engaging patients in research as well as to review the established and envisioned advantages and strategies for patient-researcher partnerships. The authors of this article, which include a patient and 4 researchers in kidney disease, discuss the expected benefits and opportunities for patient engagement in their re...

Thyroid cancers coexisted with kidney cancer in a patient is an unusual event. Here, we described a case of 35-year-old woman with synchronous occurrence of primary papillary carcinoma and follicular carcinoma of the thyroid, accompanied by renal cell carcinoma and solitary fibrous tumor of the kidney, which has not been reported in literature to our best knowledge. Its clinical and pathologica...

A 63-year-old woman with abdominal pain and melena developed a palpable, purpuric rash and acute kidney injury. Skin and kidney biopsy confirmed Henoch-Schönlein purpura. Upper endoscopy revealed diffuse, circumferential, black-appearing mucosa of the esophagus consistent with acute esophageal necrosis (AEN), also known as black esophagus. AEN is a very rare cause of gastrointestinal hemorrhage...