non-alcoholic steatohepatitis is a form of chronic hepatitis. fatty degeneration may involve liver focally or as a whole. the patient was a 41-year-old woman who was diabetic and admitted in buali hospital in ghazvin because of right flank pain, fever, vomiting and diarrhea. the patient was treated as pyelonephriris. liver function tests were as below: alt: 62 (40) ast: 54 (40), alkaline phosoh...

PURPOSE The L1 cell adhesion molecule is overexpressed in many human carcinomas. The objectives of the study were to provide a comprehensive description of L1 distribution in human kidney and to establish the prognostic relevance of L1 expression in renal cell carcinomas (RCC). EXPERIMENTAL DESIGN Using two antibodies to the extracellular part and the cytoplasmic domain, respectively, we firs...

BACKGROUND Renal cell carcinoma accounts for 90% of renal neoplasms and metastatic disease is common. One third of newly diagnosed cases will have synchronous metastases at diagnosis and further 25-50 % will develop metachronous disease. CASE PRESENTATION This study presents two new cases of gallbladder metastasis from renal cell carcinoma (RCC) from our institution and reviews the published ...

Small-cell lung cancer (SCLC) is an aggressive cancer with high metastatic ability and novel strategies against the metastasis are urgently needed to improve SCLC treatment. However, the mechanism of metastasis of SCLC remains largely to be elucidated. For further studies of SCLC metastasis, we developed a new orthotopic transplantation model in mice. We established a GFP-labeled subline from t...

Overexpression of galectin-3 in a variety of cancer cell lines has been shown to correlate with tumor progression and metastasis. In this study, we investigated the expression of galectin-3 in clear cell renal cell carcinoma (CC-RCC) and evaluated the relationship between galectin-3 expression levels and the clinicopathological features of CC-RCC. Expression of galectin-3 in the kidney cancer c...

Abstract Background Ewing’s sarcoma is categorized as small round cell aggressive tumor which commonly occurs in bone and soft tissue. Primary renal an extremely rare entity accounts for less than 1% of masses. It characterized by a very course, with few reported cases the literature. indistinguishable from carcinoma on anatomical imaging therefore need histopathological correlation confirmatio...

Non-spine bone metastasis accounts for approximately 20% of all skeletal metastases, but little data have been published that focused on bone metastasis to the pelvis and extremities as an initial manifestation of cancer. We determined 1) clinicopathologic characteristics of patients who presented with non-spine bone metastasis of unknown primary malignancy, and 2) process by which the diagnosi...