The knowledge literature suggests that transferring knowledge leads to synergistic cost advantages, better implementation of organizational strategies, and competitive advantage. Organizations are implementing corporate universities to aid in knowledge transfer. There is no standardized definition for corporate universities, but rather models that allow organizations to customize them to meet t...

Consistent reports of the positive relationship between regular physical activity and immunosenescence have generated much excitement in the field of exercise immunology. It is generally accepted that natural killer (NK) cell activity per NK cell decreases with age; decreases in NKCA have been associated with infection and death in the aged. The effects of exercise and training on natural kille...

Natural killer cells belong to the family of innate lymphoid cells comprising the frontline defense against infected and transformed cells. Development and activation of natural killer cells is highly dependent on interleukin-15 signaling. However, very little is known about the transcription program driving this process. The transcription factor Runx3 is highly expressed in natural killer cell...

The use of Pichia membranifaciens CYC 1106 killer toxin against Botrytis cinerea was investigated. This strain exerted a broad-specificity killing action against other yeasts and fungi. At pH 4, optimal killer activity was observed at temperatures up to 20 degrees C. At 25 degrees C the toxic effect was reduced to 70%. The killer activity was higher in acidic medium. Above about pH 4.5 activity...

Behavior of killer whales feeding on herring schools was recorded with a high frequency (455 kHz) sonar and recorded on a SVHS tape. Synchronization of surfacing behavior of killer whales was analyzed from 8 mm videotapes recorded between 1990–92. Two different feeding techniques, carousel feeding, where killer whales cooperatively herd herring schools into a tight ball towards the surface and ...

BACKGROUND Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines and investigated the mechanisms involved. DESIGN AND METHODS Peripheral blood mononuclear cells from six healthy donors were used to generate a...

BACKGROUND Natural killer cells have been demonstrated to exert remarkable graft-versus-leukemia effects after haploidentical transplantation. Acquisition of both, inhibiting and activating, receptors on developing natural killer cells is an important step in their functional maturation. Here, we report on the reconstitution of natural killer receptors after haploidentical transplantation of T-...

Dear Editor, A 35-year-old man presented with severe headache and left sided hemiparesis since one day prior to admission. He reported frequent bouts of oral and genital aphthous ulcers, an attack of deep venous thrombosis of left lower extremity, one episode of right knee arthritis, and several attacks of headache, neck rigidity, and fever. He had been a victim of mustard-gas poisoning at the ...

2010 John Wiley & Sons A/S Immunological Reviews 0105-2896 Granule-mediated cytolysis is undoubtedly the most important effector function of CD8 T cells and natural killer (NK) cells. After a killer cell recognizes its target, the cytotoxic granules, which are specialized secretory lysosomes that store the death-inducing proteins, migrate to the immunological synapse (IS). The cytotoxic granule...