نتایج جستجو برای: klatskin tumor

تعداد نتایج: 428022  

2014
Chiyoko Makita Tatsuya Nakamura Akinori Takada Kanako Takayama Motohisa Suzuki Yojiro Ishikawa Yusuke Azami Takahiro Kato Iwao Tsukiyama Yasuhiro Kikuchi Masato Hareyama Masao Murakami Nobukazu Fuwa Masaharu Hata Tomio Inoue

BACKGROUND We examined the efficacy and toxicity of proton beam therapy (PBT) for treating advanced cholangiocarcinoma. METHODS The clinical data and outcomes of 28 cholangiocarcinoma patients treated with PBT between January 2009 and August 2011 were retrospectively examined. The Kaplan-Meier method was used to estimate overall survival (OS), progression-free survival (PFS), and local contro...

Journal: :International journal of molecular sciences 2015
Andrej Wagner Marcus Wiedmann Andrea Tannapfel Christian Mayr Tobias Kiesslich Gernot W Wolkersdörfer Frieder Berr Johann Hauss Helmut Witzigmann

Hilar cholangiocarcinoma (CC) is non-resectable in the majority of patients often due to intrahepatic extension along bile duct branches/segments, and even after complete resection (R0) recurrence can be as high as 70%. Photodynamic therapy (PDT) is an established palliative local tumor ablative treatment for non-resectable hilar CC. We report the long-term outcome of curative resection (R0) pe...

2016
Ichiro Yasuda

Endoscopic biliary stenting is a well-established palliative procedure for treating obstructive jaundice in patients with unresectable hilar cholangiocarcinoma. Plastic tube stents (PS) have been widely used for the procedure, but self-expandable metallic stents (SEMSs) are becoming increasingly popular because of the associated longer patency. However, there are several unanswered questions re...

Journal: :Antimicrobial agents and chemotherapy 1985
J I Blenkharn N Habib D Mok L John G A McPherson R N Gibson L H Blumgart I S Benjamin

The biliary excretion of piperacillin has been assessed in 11 patients with obstructive jaundice due to hilar cholangiocarcinoma. After a 1-g intravenous dose administered 30 min before preliminary percutaneous transhepatic cholangiography, no drug was detected in the bile of seven patients; in four others, drug concentrations were far below the corresponding level in serum. After a period of e...

2014
Hui Wang Haolu Wang Tao Chen Xiaowen Liang Yanyan Song Jian Wang

BACKGROUND The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) model, its Portsmouth (P-POSSUM) modification and the Estimation of physiologic ability and surgical stress (E-PASS) are three surgical risk scoring systems used extensively to predict postoperative morbidity and mortality in general surgery. The aim was to undertake the first study...

2014
Tae Hoon Lee Jong Ho Moon Sang-Heum Park

Endoscopic palliative biliary drainage is considered as a gold standard treatment in advanced or inoperable hilar cholangiocarcinoma. Also, metal stents are preferred over plastic stents in patients with >3 months life expectancy. However, the endoscopic intervention of advanced hilar obstruction is often more challenging and complex than that of distal malignant biliary obstructions. In this l...

Journal: :Digestive surgery 2004
Hariharan Ramesh Kuruvilla Kuruvilla Ambadi Venugopal Vijayalakshmi Lekha George Jacob

BACKGROUND/AIM Major liver resection has improved the resectability rate of hilar cholangiocarcinomas, but morbidity and mortality may be significant. The aim of this study was to assess the value of parenchyma-conserving liver resection (resection of bile duct with liver segments I and IVb; PCLR) in hilar cholangiocarcinoma. METHODS Retrospective analysis of prospectively collected data. Fac...

Journal: :Journal of Hepato-Biliary-Pancreatic Surgery 2008
Tadahiro Takada Masaru Miyazaki Shuichi Miyakawa Kazuhiro Tsukada Masato Nagino Satoshi Kondo Junji Furuse Hiroya Saito Toshio Tsuyuguchi Fumio Kimura Hideyuki Yoshitomi Satoshi Nozawa Masahiro Yoshida Keita Wada Hodaka Amano Fumihiko Miura

Apart from periampullary carcinoma, the prognosis of biliary tract carcinomas, including hilar cholangiocarcinoma, extrahepatic biliary tract carcinoma, and gallbladder carcinoma, remains poor. Sophisticated diagnostic skills and treatment methods and their application are naturally required to achieve better treatment results for biliary tract carcinomas. However, it is not too much to say tha...

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