This article comprises detail information about Lasparaginase, encompassing topic such as various sources of Lasparaginase, mechanism and properties of L-asparaginase. Also describe the production, cultivation and purification of Lasparaginase along with information about the application of Lasparaginase. L-asparaginase catalyzes the conversion reaction to convert asparagine to aspartic acid an...

The effect of aspartic acid on the adsorption of Pb(II), Cu(II), Zn(II), Co(II), and Mn(II) on kaolinite at 25 degrees C in the presence of 5 mM KNO3 was investigated by means of potentiometric titrations and adsorption measurements over a range of pH and concentration. Data were modeled by extended constant capacitance models. Aspartic acid slightly enhanced the adsorption of Pb(II), Zn(II), a...

Virtanen and Laine (1937) were the first to suggest the existence of an aspartic acid decarboxylase in Rhizobium trifolii, by the isolation of beta-alanine from a 47-day fermentation mash containing aspartic acid. Shive and Macow (1946), working with hydroxyaspartic acid as a competitive analogue for aspartic acid in the metabolism of Escherichia coli, found that the addition of this compound t...

This study demonstrates the development of effective modified films for As(III) removal from aqueous solution. Low-density polyethylene (LDPE) were grafted by c (Sty/MAn) co-monomer using gamma irradiation. The functionalized six amine groups including semicarbazide, L-aspartic acid, 2-aminopyridine, thiosemicarbazide, hydroxylamine-HCl, and thiourea. grafting was verified FTIR that shows MAn c...

There has been focus upon the study of stability constants amino acids with metal ions since they processes antibacterial activities. The ternary complexes were determined by pH metric analysis in aqueous solution at 25.0 0C between ligands (Mercaprosuccinicacid (MSA), Glycine (GLY), L-Aspartic acid (ASP) and L-Asparagine (ASN)) some transition ions(Co(II), Ni(II), Cu(II) Zn(II)) varying Ethyle...

Ko143 is a tetracyclic, synthetic analog of the fungal metabolite fumitremorgin C. potent and specific inhibitor membrane-bound efflux transporter ABCG2, it reverses ABCG2-mediated drug resistance in cancer cells. Here, we describe an improved synthesis that relies on highly selective, substrate-controlled reduction imine formed Bischler–Napieralski reaction with amide derived from 6-methoxy-l-...

An enzyme, carboxypeptidase G1, extracted from a strain of Pseudomonas stutzeri, has been isolated which hydrolyzes the carboxyl-terminal glutamate from both reduced and nonreduced folate derivatives, with K, values between 1.1 and 18.1 X 10e6 M. This enzyme also hydrolyzes the COOH-terminal glutamate of oligopeptides and N-benzyloxycarbonyl glutamates; it demonstrates lesser activity against a...

Hydroxy amino acids (HAAs) are of unique value in the chemical and pharmaceutical industry with antiviral, antifungal, antibacterial, anticancer properties. At present, hydroxylated most studied tryptophan, lysine, aspartic acid, leucine, proline, etc., some their derivatives. The hydroxylation is inextricably linked to catalysis various biological enzymes, such as tryptophan hydroxylase, L-pip...