Mixed performance control problems have been the object of much attention lately. These problems allow for capturing different performance specifications without resorting to approximations or the use of weighting functions, thus eliminating the need for trial-and-error-type iterations. In this paper we present a methodology for designing mixed l1=H1 controllers for MIMO systems. These controll...

Recent studies on L2 acquisition focus how interface-related properties are acquired at the end state grammars. Proposed as part of this theme, Interface Hypothesis (Sorace & Filiaci, 2006; Sorace, 2011) claims that syntax-discourse interface is particularly challenging to acquire, irrespective L1 and speakers. On other hand, Full Transfer / Access (Schwartz Sprouse, 1996) predicts L1-const...

The focus of thesis is on (i) designing of bidentate chalcogenoether ligands (ii) exploring their coordination chemistry with Pd(II), (η-benzene)Ru(II) and (ηpentamethylcyclopentadiene) Rh(III) / Ir(III) and (iii) investigating the designed metal complexes for C−C coupling reactions, NMO based oxidation of alcohols, Oppenauer-type oxidation of alcohols and transfer hydrogenation of carbonyl com...

Peroxisome proliferator-activated receptor (PPAR)-gamma plays an important role in adipogenesis. However, the functions of PPAR-gamma in differentiated adipocytes have remained unclear. The role of PPAR-gamma in mature 3T3-L1 adipocytes was therefore investigated by overexpression of a dominant negative mutant of this protein (PPAR-gamma-DeltaC) that lacks the 16 COOH-terminal amino acids and t...

Optical tomography is an emerging and important molecular imaging modality. The aim of optical tomography is to reconstruct optical properties of human tissues. In this paper, we focus on reconstructing the absorption coefficient based on the radiative transfer equation (RTE). It is an ill-posed parameter identification problem. Regularization methods have been broadly applied to reconstruct th...

New therapeutic modalities are needed for ovarian cancer, the most lethal gynecologic malignancy. Recent clinical trials have demonstrated the impressive therapeutic potential of adoptive therapy using chimeric antigen receptor (CAR)-redirected T cells to target hematological cancers, and emerging studies suggest a similar impact may be achieved for solid cancers. We sought determine whether ge...

Recurrent solid malignancies are often refractory to standard therapies. Although adoptive T cell transfer may benefit select individuals, the majority of patients succumb to their disease. To address this important clinical dilemma, we developed a mouse melanoma model in which initial regression of advanced disease was followed by tumor recurrence. During recurrence, Foxp3(+) tumor-specific CD...

This paper explores the ways in which the transfer of assumptions from first language (L1) writing can help the process of writing in second language (L2). In learning second language writing skills, learners have two primary sources from which they construct a second language system: knowledge and skills from first language and input from second language. To investigate the relative impact of ...

The present research aims to examine the effects of using culturally oriented texts in project-based classes on the views of EFL university students regarding their L1 culture. To this end, three experimental groups of intermediate EFL freshmen, assigned to classes A, B and C, participated in this study. Each of the classes were presented with reading passages focused on L1 culture, L2 culture,...

Investigating transfer of one’s pragmatic knowledge of first language to his second or foreign language has been one of the areas of interest for researchers. However, there are contradictory results even within the scarce studies which have addressed transferability. This study was an attempt to investigate perceived pragmatic transferability of L1 refusal strategies by Persian EFL learners. S...