نتایج جستجو برای: lactoferricin
تعداد نتایج: 210 فیلتر نتایج به سال:
Increasing attention is being paid to chemopreventive agents for individuals at high risk of cancer. We have concentrated on bovine lactoferrin (bLF), an 80 kDa iron-binding glycoprotein known to have anti-microbial and immunoprotective effects. Lactoferrin is particularly abundant in colostrum, and is also present in tears, saliva and seminal and uterine secretions. However, only little is kno...
Bovine lactoferricin (LfcinB) has potent antibacterial, antifungal and antiparasitic activities but is also hemolytic. Our objective was to identify LfcinB17-31 derivatives with reduced hemolysis and improved antimicrobial activity via substituting Cys3, Arg4, Gln7, Met10, and Gly14 with more hydrophobic residues. Two peptides, Lfcin4 and Lfcin5, showed higher activity against Staphylococcus au...
Bovine lactoferricin (LfcinB) is a cationic peptide that selectively induces caspase-dependent apoptosis in human leukemia and carcinoma cell lines. Ceramide is a second messenger in apoptosis signaling that has been shown to increase the cytotoxicity of various anti-cancer drugs. In this study, we determined whether manipulation of intracellular ceramide levels enhanced LfcinB-induced apoptosi...
s of the 7th International Conference on Lactoferrin / Résumés de la 7e Conférence internationale sur la lactoferrine N. Kumagai, S. Tsunematsu, H. Hamano, K. Yamauchi, and K. Tsuchimoto 385 Oral administration of lactoferrin enhances viral decline in patients with genotype-1B-related chronic hepatitis C treated with Peginterferon a-2B plus ribavirin T. Kuhara, K. Yamauchi, and M. Takase 385 Or...
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