Nonalcoholic steatohepatitis (NASH) is a liver disease associated with metabolic syndrome. The aim of this work was to examine whether eucalyptus (Eucalyptus globulus) leaf extract (ELE) and banaba (Lagerstroemia speciosa L.) leaf extract (BLE) inhibited NASH induced by excessive ingestion of fructose in rats. Wistar rats were divided into four groups according to four distinct diets: starch di...

Corosolic acid (CA), a triterpenoid compound isolated from Lagerstroemia speciosa L. (Banaba) leaves, exerts anti-inflammatory effects by regulating phosphorylation of interleukin receptor-associated kinase (IRAK)-2 via the NF-κB cascade. However, the protective effect of CA against endotoxic shock has not been reported. LPS (200 ng/mL, 30 min) induced phosphorylation of IRAK-1 and treatment wi...

An attempt was made to analyse the antimicrobial potential of 2 medicinally important plants viz., Lagerstroemia indica and Annona reticulata leaf extracts against human bacterial pathogens viz., Klebsiella pneumoniae, Staphylococcus auerus, Salmonella typhi, Proteus vulgaris and Pseudomonas aeruginosa. Antimicrobial study was carried out by disc diffusion method against the pathogens by using ...

Corosolic acid (CA), contained in the leaves of the banaba plant (Lagerstroemia speciosa L.), is a pentacyclic triterpene, and has hypoglycemic effects. The effects of CA on dietary hypercholesterolemia and hepatic steatosis were assessed in KK-Ay mice, an animal model of type 2 diabetes. Two kinds of high cholesterol diet with or without 0.023% CA, were prepared for the study. KK-Ay mice were ...

Diabetes mellitus is a metabolic non-communicable chronic disease in which the body's ability to process glucose impaired, resulting higher blood levels. If not controlled, this can lead severe complications. Various plants with medicinal properties treat diseases, such as diabetes, due therapeutically important phytochemicals and bioactive compounds. This study investigated effect of antidiabe...

INTRODUCTION A number of natural compounds have individually demonstrated to improve glucose and lipid levels in humans. AIM To  evaluate the short-term glucose and lipid-lowering activity in subjects with impaired fasting glucose. METHODS To assess the effects of a combination of nutraceuticals based on Lagerstroemia speciosa, Berberis aristata, Curcuma longa, Alpha-lipoic acid, Chrome pic...

Banaba (Lagerstroemia speciosa Pers) leaves has been used as tea or decoction type in the Philippines for blood sugar control and used in the treatment of diabetes in India and contain a treterpenoid compound know as a corosolic acid which can promote the absorption and utilization of glucose in the cell by transporting the stimulated glucose. As such, banaba plays a role in regulating levels o...