نتایج جستجو برای: lap joint interface

تعداد نتایج: 394655  

2015
René Huber Thomas Panterodt Bastian Welz Martin Christmann Judith Friesenhagen Andreas Westphal Daniel Pietsch Korbinian Brand Thomas Langmann

The transcription factor C/EBPβ plays a key role in monocytic differentiation and inflammation. Its small isoform LIP is associated with proliferation at early premonocytic developmental stages and regulated via mTOR-dependent signalling. During later stages of (pre)monocytic differentiation there is a considerable increase in the large C/EBPβ isoforms LAP*/LAP which inhibit proliferation thus ...

Journal: :Advanced healthcare materials 2014
Xinpeng Ma Xiumei Huang Gang Huang Longshan Li Yiguang Wang Xiuquan Luo David A Boothman Jinming Gao

β-Lap prodrug micelle strategy improves the formulation properties of β-lap therapeutics. The resulting micelles yield apparent high β-lap solubility (>7 mg mL(-1) ), physical stability, and ability to reconstitute after lyophilization. In the presence of esterase, β-lap prodrugs are efficiently converted into parent drug (i.e., β-lap), resulting in NQO1-dependent lethality of NSCLC cells.

2014
Jayashri Mahalingam Chun-Yen Lin Jy-Ming Chiang Po-Jung Su Yu-Yi Chu Hsin-Yi Lai Jian-He Fang Ching-Tai Huang Yung-Chang Lin Derya Unutmaz

Latency-associated peptide (LAP) - expressing regulatory T cells (Tregs) are important for immunological self-tolerance and immune homeostasis. In order to investigate the role of LAP in human CD4⁺Foxp3⁺ Tregs, we designed a cross-sectional study that involved 42 colorectal cancer (CRC) patients. The phenotypes, cytokine-release patterns, and suppressive ability of Tregs isolated from periphera...

Journal: :International journal of sports physiology and performance 2011
Yann Le Meur Thierry Bernard Sylvain Dorel Chris R Abbiss Gérard Honnorat Jeanick Brisswalter Christophe Hausswirth

PURPOSE The purpose of the present study was to examine relationships between athlete's pacing strategies and running performance during an international triathlon competition. METHODS Running split times for each of the 107 finishers of the 2009 European Triathlon Championships (42 females and 65 males) were determined with the use of a digital synchronized video analysis system. Five camera...

Journal: :TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A 1988

Journal: :International Journal of Solids and Structures 2015

Journal: :International Journal of Mechanical Engineering and Robotics Research 2021

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