Introduction: The activated B-cell (ABC) type of diffuse large lymphoma (DLBCL) is associated with poor response to second line therapy and characterized by constitutive activation the NF-κB pathway. MALT1 a central signaling molecule which promotes via dual protease scaffold functions. Clinical interest focuses on allosteric inhibitors, one being tested in phase I trial, however this approach ...

fab (french – american- british) group determined a diagnostic classification for leukemia's. but in spite of some reports on different clinical findings and prognosis of hmc and lgl there is no place for hand- mirror cell leukemia and lgl leukemia in this classification. on the other hand, there are different ideas about causes of hand mirror cell and about different changes of large granlar l...

  A male patient with acute renal failure (ARF) due to large B-cell non-Hodgkin lymphoma infiltration of kidney is presented. The diagnosis was suspected because of coincidence of ARF and tumor lysis syndrome non-responsive to conservative renal therapies. A renal biopsy confirmed diagnosis and appropriate chemotherapy led to complete improvement of renal function.  

The RNA polymerase III–specific TFIIIB complex is targeted by oncogenes and tumor suppressors, specifically the subunits BRF1, BRF2, TBP. Currently, it unclear if subunit BDP1 universally deregulated in human cancers. We performed a meta-analysis of patient data Oncomine database to analyze alterations Herein, we report possible role for non-Hodgkin’s lymphoma (NHL) first time. To best our know...

Cutaneous round cell tumors have been classified as mast cell tumor (MCT), histiocytoma (HCT), lymphosarcoma, undif-ferentiated round cell tumors and occasionally rhabdomyosarcoma in veterinary medicine. An adult cock (Gallus domesticus) showing a large solitary integument mass raised on dorso bilateral of cervical part, extending to intercapsular and cranial mid part of the back was referred t...

neurological signs and symptoms are commonly associated with both hodgkin’s and non-hodgkin’s lymphoma and are mostly attributed to either direct lymphomatous involvement of the nervous system, either as a result of extension to the spinal cord or nerves, or due to infiltration by lymphoma cells and drug toxicity. guillain-barre syndrome and its variants have been reported very infrequently in ...