Dystonia is a symptom defined by involuntary and irregular contractions of the muscles, which cause movement disorders and postural problems. Deep brain stimulation (DBS) in globus pallidus interna (GPi) is a good option for controlling dystonia. DBS has already been shown to have significant effects on primary dystonia as well as Parkinson's disease. Dystonia is very difficult to manage, as se...

We report on a patient with sporadic Creutzfeldt-Jakob disease (CJD) who showed dystonia, periodic myoclonus, and periodic sharp wave complexes (PSWCs) on EEG. The EEG-EMG polygraphic study revealed that dystonia appeared without relation to periodic myoclonus and PSWCs and that dystonia EMGs were strongly suppressed after periodic myoclonus EMGs. These findings suggest that dystonia has a path...

Dystonia is a heterogeneous movement disorder and has been defined as 'a syndrome of sustained muscle contractions, frequently causing twisted and repetitive movements, or abnormal postures'. The classification of dystonia has developed along with increasing knowledge, and different schemes have been suggested, including age at onset, body distribution, and etiology as the main differentiating ...

INTRODUCTION Musician's dystonia is a task-specific loss of voluntary motor control of the fingers or the embouchure. In contrast to pianists' dystonia, which can be objectively assessed based on movement kinematics and muscular activities, no objective quantitative measure has been established for embouchure dystonia. METHODS We focused on acoustic signals, and investigated, whether the fluc...

Background: Dopa-responsive dystonia associated with mutations in the GCH1 gene (DYT5) is classically described as autosomal dominant but rare cases recessive inheritance have been reported. The (AD) form characterized by a childhood onset and predominates females. It usually starts gait disturbance foot (segmental dystonia) fluctuation of symptoms during day, parkinsonism can be present. treat...

Eight cases of persistent dystonia appearing one to 14 years after non-progressive cerebral insults are described. Five were due to perinatal anoxia, one to trauma, and two to cerebral infarction. This phenomemon of delayed-onset dystonia has not been described previously, although review of earlier literature reveals several probable examples. Delayed-onset dystonia due to perinatal anoxia is ...

Background Systematic perceptual distortions of tactile space have been documented in healthy adults. In isolated focal dystonia impaired spatial somatosensory processing is suggested to be a central pathophysiological finding, but the structure for different body parts has not previously explored. Objectives The objective this study was assess organization with novel behavioral paradigm distan...

Dystonia is a syndrome of sustained muscle contractions, frequently causing repetitive movements or abnormal postures. They are classified by age of onset, by aetiology and by distribution. Younger the age of onset, the more Likely that the dystonia will become severe and involve multiple parts of the body (Marsden et al., 1976). Approximately one third of all patients with dystonia have sympto...

Indirect evidence suggests that the thalamus contributes to abnormal movements occurring in patients with dystonia (dystonia patients). The present study tested the hypothesis that thalamic activity contributes to the dystonic movements that occur in such patients. During these movements, spectral analysis of electromyographic (EMG) signals in flexor and extensor muscles of the wrist and elbow ...

OBJECTIVE Spasmodic dysphonia is a focal dystonia of the larynx with heterogeneous manifestations and association with familial risk factors. There are scarce data to allow precise understanding of etiology and pathophysiology. Screening for dystonia-causing genetic mutations has the potential to allow accurate diagnosis, inform about genotype-phenotype correlations, and allow a better understa...