BACKGROUND The purpose of this study was to use time trade-off to assess the factors influencing patients' decisions in advanced laryngeal cancer. Time trade-off is a well-established method of assessing how individuals value a particular health state. METHODS We developed vignettes depicting life after chemoradiotherapy or laryngectomy. One hundred fourteen participants ranked them, assigned...

BACKGROUND Cancer of the larynx in the intermediate/advanced stage still presents a major challenge in terms of controlling the disease and preserving the organ. Among therapeutic options, open partial horizontal laryngectomy is proposed as a function-sparing surgical technique. METHODS We analyzed the clinical outcomes of 555 patients with laryngeal cancer staged pT3 to pT4a who underwent op...

Early-stage laryngeal cancers may be treated with partial surgery thanks to advances in diagnosis and surgery. The aim of our study is to compare the degree of voice disorders and respiratory function between healthy volunteers and patients that underwent a partial laryngectomy surgery. 30 patients who underwent partial laryngectomy due to laryngeal cancer and 30 healthy volunteers were include...

OBJECTIVES/HYPOTHESIS The role of tumor volume in T4a laryngeal cancer remains unclear among different treatment modalities. Using tumor volumetry, we investigated the impact of primary tumor volume on this subset of patients. STUDY DESIGN Retrospective cohort study of 62 T4a laryngeal cancer patients. METHODS From October 2002 to September 2010, 48 patients were treated with definitive che...

BACKGROUND Laryngeal squamous cell carcinoma (SCC) accounts for 1.9% of cancers worldwide. Most of these are diagnosed in the early stages (T1-T2, and N0). For these, a larynx preserving/conserving option is preferable. Beyond transoral laser microsurgery (TLM), open partial horizontal laryngectomy is a function-sparing surgical technique used to treat laryngeal SCC. METHODS We retrospectivel...

OBJECTIVES/HYPOTHESIS To develop a technique for computer enhanced robotic transoral supraglottic partial laryngectomy in the canine model. STUDY DESIGN Surgical procedure on the larynx in a canine model with a commercially available surgical robot. METHODS With use of the da Vinci Surgical Robot (Intuitive Surgical, Inc., Sunnyvale, CA), the supraglottic partial laryngectomy was performed ...

BACKGROUND We examined the relation of tobacco and alcohol consumption after total laryngectomy with overall survival (OS). METHODS Tobacco and alcohol consumption was assessed at 5 time points after total laryngectomy. Patients were followed up for survival until December 31, 2014. A multivariate Cox regression was fitted to test for differences in OS. RESULTS Three hundred fifty-nine pati...

BACKGROUND The purpose of this study was to compare total laryngectomy versus concurrent chemoradiotherapy (CRT) for functional and long-term quality of life (QOL) outcomes in patients with pharyngolaryngeal carcinoma. METHODS Among 145 patients treated for advanced pharyngolaryngeal cancer by CRT or total laryngectomy between 2000 and 2008, 47 patients who had completed treatment for >1 year...

OBJECTIVE To evaluate functional and oncologic results in patients who underwent unilateral arytenoidectomy during supracricoid partial laryngectomy. DESIGN Retrospective analysis of medical records. SETTING Tertiary care referral center. PATIENTS One hundred sixteen patients who had received supracricoid partial laryngectomy. MAIN OUTCOME MEASURES Functional and oncologic results in pa...

Objective: To determine the prevalence of, and describe transglottic cancer with thyroid cartilage invasion as a possible risk for, thyroid gland invasion in a series of patients with laryngeal carcinoma who underwent total laryngectomy with thyroidectomy. Methods: Design: Retrospective Case Series Setting: Tertiary Government Training Hospital Participants: 61 laryngeal carcinoma patients who ...