Interaction of epidermal growth factor (EGF) with its specific receptor (EGFR) was explored in the intact rat small intestine and in highly purified isolated enterocyte membrane preparations. Despite the fact that the EGF ligand is known to be present at physiological concentrations within the intestinal cavity, no significant binding of the ligand to the brush border surface was observed. Inst...

We have adopted a numerical method from computational fluid dynamics, the Lattice Boltzmann Method (LBM), for real-time simulation and visualization of flow and amorphous phenomena, such as clouds, smoke, fire, haze, dust, radioactive plumes, and air-borne biological or chemical agents. Unlike other approaches, LBM discretizes the micro-physics of local interactions and can handle very complex ...

While the lattice Boltzmann method (LBM) has become a powerful numerical approach for solving complex flows, the standard LBM typically uses a square lattice grid in two spatial dimensions and cubic lattice grid in three dimensions. For inhomogeous and anisotropic flows, it is desirable to have a LBM model that utilizes a rectangular grid. There were two previous attempts to extend the multiple...

Lean body mass (LBM) encompasses all metabolically active organs distributed into visceral and structural tissue compartments and collecting the bulk of N and K stores of the human body. Transthyretin (TTR) is a plasma protein mainly secreted by the liver within a trimolecular TTR-RBP-retinol complex revealing from birth to old age strikingly similar evolutionary patterns with LBM in health and...

In the last two decades, the Lattice Boltzmann method (LBM) has emerged as a promising tool for modelling the Navier-Stokes equations and simulating complex fluid flows. LBM is based on microscopic models and mesoscopic kinetic equations. In some perspective, it can be viewed as a finite difference method for solving the Boltzmann transport equation. Moreover the Navier-Stokes equations can be ...

OBJECTIVE To compare aerobic capacity of young and adult elite soccer players using appropriate scaling procedures. METHODS Twenty four male adult (mean (SD) age 24 (2) years, weight 75.7 (7.2) kg, VO2max 66.6 (5.2) ml/lbm/min, where lbm is lean body mass in kg) and 21 youth (14 (0.4) years, 60.2 (7.3) kg, 66.5 (5.9) ml/lbm/min) elite soccer players took part in the study. Allometric equation...

BACKGROUND AND AIMS Nutritional status is a prognostic factor for survival in amyotrophic lateral sclerosis (ALS) patients. We investigated the contribution of some of the components contributing to resting energy expenditure (REE) in order to determine whether potentially higher energy needs should be considered for these patients. METHODS Thirty three ALS patients and 33 age- and gender-mat...

We construct a system of nonequilibrium entropy limiters for the lattice Boltzmann methods (LBM). These limiters erase spurious oscillations without blurring of shocks, and do not affect smooth solutions. In general, they do the same work for LBM as flux limiters do for finite differences, finite volumes and finite elements methods, but for LBM the main idea behind the construction of nonequili...

BACKGROUND The beneficial effects of testosterone treatment (TT) are debated. METHODS Double-blinded, placebo-controlled study of six months TT (gel) in 54 men aged 60-78 with bioavailable testosterone (BioT) <7.3 nmol/L and waist >94 cm randomized to TT (50-100 mg/day, n = 20), placebo (n = 18), or strength training (ST) (n = 16) for 24 weeks. Moreover, the ST group was randomized to TT (n =...

The recently introduced inertial-range IR consistent Smagorinsky model and the classical Smagorinsky model are applied to the large-eddy simulation LES of decaying homogeneous isotropic turbulence based on the lattice Boltzmann method LBM , which is implemented using the 19-velocity D3Q19 lattice model. The objectives of this study are to examine the effectiveness of the LES-LBM technique for s...