In this paper, we study the group Pext(C, A) for locally compact abelian (LCA) groups A and C. Sufficient conditions are established for Pext(C, A) to coincide with the first Ulm subgroup of Ext(C, A). Some structural information on pure injectives in the category of LCA groups is obtained. Letting C denote the class of LCA groups which can be written as the topological direct sum of a compactl...

Leukocyte common antigens (LCAs, also known as T200 and CD 45) are integral membrane proteins expressed exclusively on hematopoietic cells. These molecules exhibit varying molecular masses and epitopes when expressed in different cell types. To determine the genetic bases for the generation of this diversity, three classes of human LCA cDNA clones that are different near their 5' ends have been...

The reduction in transportation costs when travelling with a low-cost airline (LCA) seems to have modified the composition of the trip budget. An understanding of expenditure composition when comparing LCA and legacy airline travellers is vital for destination marketers. Using micro official statistics data for air travellers to Spain in 2010 and the compositional data analysis (CODA) methodolo...

Percutaneous coronary intervention (PCI) for anomalous left coronary artery (LCA) originating from the noncoronary cusp (NCC) is challenging, as it poses difficulties with the engagement of the guiding catheter and the establishment of backup support. This report examines the case of a 69-year-old woman with unstable angina of anomalous LCA origin. The computed tomography showed a diffuse plaqu...

In the context of this problem, we need to be very specific on choosing an uncovered sk, tk-path at each iteration. Fix a vertex r of G as the root of the tree. For each pair (si, ti), let LCA(si, ti) denote the least common ancestor of si and ti, which is the vertex at the intersection of the paths from si to r and from ti to r. Note that LCA(si, ti) could be si or ti. Let d(si, ti) denote the...

USP2a is a deubiquitinase responsible for stabilization of cyclin D1, a crucial regulator of cell-cycle progression and a proto-oncoprotein overexpressed in numerous cancer types. Here we report that lithocholic acid (LCA) derivatives are inhibitors of USP proteins, including USP2a. The most potent LCA derivative, LCA hydroxyamide (LCAHA), inhibits USP2a, leading to a significant Akt/GSK3β-inde...

Economic, social and environmental dimensions are usually accepted as the three pillars of sustainable development. However, current methodologies for the assessment of the sustainability of product systems fail to cover economic, environmental and social parameters in a single combined approach. Even though the perfect methodology is still far off, this article attempts to provide insights on ...

BACKGROUND Leber congenital amaurosis (LCA) is the earliest and most severe inherited retinal degeneration. Isolated forms of LCA frequently result from mutation of the CEP290 gene which is expressed in various ciliated tissues. METHODS Seven LCA patients with CEP290 mutations were investigated to study otorhinolaryngologic phenotype and respiratory cilia. Nasal biopsies and brushing were per...

To clarify the natural history and management of patients with aberrant origin of a coronary artery from the aorta, we reviewed 18 patients whose right (RCA) or left (LCA) coronary artery arose aberrantly and passed between the aorta and right ventricular infundibulum. Nine patients had aberrant LCA. Three young males died suddenly after exertion, each with proximal focal LCA stenosis. None of ...

This paper aims to explore the potential as well as limitations of using Life Cycle Assessment (LCA) for comparing environmental impacts associated with aquaculture and other agri-food products. LCA has been used to assess environmental impacts, to identify environmentally-friendlier farming systems, to support environmental improvement, to designate benchmarking, and to develop eco-labelling c...