1. Erabutoxins a, b and c, neurotoxic proteins of a sea snake Laticauda semifasciata, were guanidinated with O-methylisourea. The amino groups of all the lysine residues and those at the N-termini of the toxins were modified. The lethal activity of the toxins decreased to 50% (erabutoxins a and b) or 17% (erabutoxin c) of the original value on the modification. The c.d. (circular dichroism) max...

ENTURY OF L IFE H APPY B IRTHDAY P AUL W EISS Paul Weiss, one of the great American philosophers of the twentieth century, celebrated his 100th birthday on 19 May. Peirceans worldwide are indebted to Paul for the crucial role he played in the 1930s in editing Peirce’s writings for the Harvard edition. The Collected Papers inaugurated Peirce scholarship, standing as the historical foundation for...

This paper discusses several unique hardware testbeds that were developed to evaluate coordination and control algorithms for missions with multiple unmanned aerial vehicles (UAVs). The first testbed uses eight rovers and two blimps operated indoors to emulate a heterogeneous fleet of aircraft. The second testbed has eight UAVs flown autonomously with commercial autopilots, which are also used ...

BACKGROUND AND OBJECTIVE: Complementary and alternative medicine (CAM) use for pediatric asthma is increasing. The authors of previous studies linked CAM use with decreased adherence to conventional asthma medicines; however, these studies were limited by cross-sectional design. Our objective was to assess the effect of starting CAM on pediatric adherence with daily asthma medications. METHODS:...

I revise the subfamily Diplazontinae to include 99 Western Palaearctic species, review morphological characters useful for species delimitation and identification, and clarify the status of some morphologically similar taxa using molecular approaches. Illustrated, dichotomous keys to the Western Palaearctic genera and species of the subfamily are presented, and the utility of the molecular mark...

BACKGROUND AND OBJECTIVE: Complementary and alternative medicine (CAM) use for pediatric asthma is increasing. The authors of previous studies linked CAM use with decreased adherence to conventional asthma medicines; however, these studies were limited by cross-sectional design. Our objective was to assess the effect of starting CAM on pediatric adherence with daily asthma medications. METHODS:...

BACKGROUND Scrub typhus is a leading cause of serious febrile illness in rural Southeast Asia. The causative agent, Orientia tsutsugamushi, is an obligate intracellular bacterium that is transmitted to humans by the bite of a Leptotrombidium mite. Research into the basic mechanisms of cell biology and pathogenicity of O. tsutsugamushi has lagged behind that of other important human pathogens. O...

On a worldwide basis, mites are important nuisance pests and some are capable of transmitting disease causing agents to humans. There are many different species of bloodsucking mites, some mites live in people’s skin (mites that cause scabies), while other species may take blood meals on human hosts. For this reason, this article has been designed to highlight disease agents vectored by mites a...