Ann E. Hyslop, MD Brian S. Droker, MD Laura A. Jansen, MD, PhD SECTION 1 A 4 month-old former full-term male infant presented with 4 days of lethargy, fussiness, low-grade fever, and dehydration, prompting hospital admission. His mother had tested positive for H1N1 influenza the week before, and treatment with oseltamivir was started. Oseltamivir treatment was started empirically in the infant,...

Cases with Hirschsprung's disease show the functional intestinal obstruction. Obstruction in these patients may lead to bacterial overgrowth with stasis and inflammation of the colon. Bacterial overgrowth can cause hyperammonemia that makes lethargy and loss of conscious and finally admitting in ICU. The purpose of this case report is to present a case that had Hirschsprung's disease and referr...

Patient 1 A 67-year-old man with hypertension and hypercholesterolemia developed sudden right hemiparesis, dysarthria and lethargy. He presented to our institution 10 h following symptom onset. During the previous 3 weeks, he had had 2 episodes of transient leg weakness and headache. Neurological examination revealed severe lethargy, right gaze palsy, right facial weakness, deviation of the ton...

Zinc is an essential mineral that can cause pathological effects whether in excess or deficiency. Zinc is a component for over 250 enzymes and is required for cell growth, cell division, and cell function. Zinc is found in muscle and bones, with the prostrate, liver, skin, and kidney having detectable levels of zinc. However, zinc present in excess or deficiency can cause significant pathology ...

OBJECTIVE To evaluate the validity of clinical and laboratory signs to serious dengue disease in hospitalized children. METHODS Retrospective cohort of children (<18 years) hospitalized with dengue diagnosis (2007-2008). Serious dengue disease was defined as death or use of advanced life support therapy. Accuracy measures and area under the receiver operating characteristic curve were calcula...

This is a case of a 33 years old Chinese lady who was previously healthy. Her lifestyle was sedentary (clerical job). Her weight was 60 kg and height 1.63 m (BMI 22.6 kg/m2). During a company motivation course she was instructed by the speaker to do 90 push-ups as a penalty for losing in one of the events. She admitted that it was tough but she managed to complete the push-ups over 5-10 minutes...

We described elsewhere that the synergistic antitumor activity of endotoxic extracts from Re mutants of gram-negative bacteria and trehalose mycolate against guinea pig syngeneic line 10 tumor was abrogated after peptide substances accompanying these extracts had been removed. This activity could be restored by combining peptide-free endotoxin either with cell wall skeleton from Bacillus Calmet...

A 58-year-old woman of European ancestry presented to a rural hospital in New South Wales in May 2014 with an 8-month history of worsening motor instability, confusion and bilateral occipital headaches associated with photophobia, lethargy and somnolence. The patient was from Geraldton in Western Australia and was staying for 2 weeks with her family in NSW. Her symptoms had started 1 month afte...

Hypothyroidism is the most common endocrine disorder in dogs. The present paper puts on record various ailments associated with primary hypothyroidism caused by thyroxine (T4) deficiency and peripheral disorders in euthyroid dogs, which mimic hypothyroidism. The study undertaken on 10,172 dogs presented at the clinics with skin and coat incongruity, revealed clinical manifestations suggestive o...

This study aimed to analyse UK pharmacovigilance data to quantify adverse events (AEs) associated with the non-steroidal anti-inflammatory drug (NSAID) molecules found in veterinary medicines authorised for use in dogs and cats. It was hypothesised that the frequency of AEs would be lower when associated with cyclo-oxygenase-2 selective (coxib), compared to non-selective (non-coxib) NSAIDs. The...