Polycythemia vera (PV) and essential thrombocythemia (ET) constitute two of the three BCR-ABL1-negative myeloproliferative neoplasms and are characterized by relatively long median survivals (approximately 14 and 20 years, respectively). Potentially fatal disease complications in PV and ET include disease transformation into myelofibrosis (MF) or acute myeloid leukemia (AML). The range of repor...

OBJECTIVE Vascular events are a common complication in patients with polycythemia vera (PV) and essential thrombocythemia (ET). This study aimed to analyze the association between PAI-1 4G/5G and ACE I/D gene polymorphisms, and leukocytosis with thrombosis in patients with PV and ET. MATERIAL AND METHODS In total, 64 patients with ET and PV were evaluated. Arterial or venous thrombosis, such ...

Stroke is the second most common cause of death and leading disability worldwide. Hemorrhagic stroke occurs in 15% cases. Increased leukocyte counts acute phase hemorrhagic are believed to be related incidence early neurological deterioration. This study aims determine relationship between increased count deterioration patients while being treated at UKI General Hospital. research analytic with...

We previously demonstrated in rabbits that various neutrophil chemotactic factors share an ability to induce recruitment of polymorphonuclear leukocytes (PMN) from bone marrow when administered intravenously (Jagels and Hugli, J Immunol 148:1119, 1992). In the study reported here, we investigated the effects of chemotactic factors on the expression of beta 2 integrins and L-selectin in vivo and...

TO THE EDITOR—The epidemiology of Clostridium difficile infection (CDI) and role of particular strain types in clinical outcome is complex. Walk et al conclude that the polymerase chain reaction (PCR) ribotypes 027 and 078 are not independent predictors of severe outcome when adjusted by the patient’s leukocyte count and albumin level [1]. Although the albumin level more clearly reflects underl...