acceptor/donor or Lewis acid-base (AB) terms, in regulating not only the rates of these reactions but also in determining the solubility behavior of the crystal, S,. For a considerable number of compounds, the solubilities show a general increase as the solidlliquid interfacial tensions (~sL) decrease, but despite suggestions to the contrary, the relationship between ysL and logs, should not ne...

The logic V is the basic logic of counterfactuals in the family of Lewis’ systems. It is characterized by the whole class of so-called sphere models. We propose a new sequent calculus for this logic. Our calculus takes as primitive Lewis’ connective of comparative plausibility : a formula A B intuitively means that A is at least as plausible as B. Our calculus is standard in the sense that each...

The Lewis blood group system comprises two main carbohydrate antigens, Le’ and Leb. Lewis typing has traditionally been based on serologic determinations using erythrocytes and saliva. Several recent studies have demonstrated that erythrocyte Lewis phenotype may change during pregnancy or disease, and inappropriate Lewis antigens have been found in both normal and neoplastic tissue. To evaluate...

The Lewis blood group system comprises two main carbohydrate antigens, Le’ and Leb. Lewis typing has traditionally been based on serologic determinations using erythrocytes and saliva. Several recent studies have demonstrated that erythrocyte Lewis phenotype may change during pregnancy or disease, and inappropriate Lewis antigens have been found in both normal and neoplastic tissue. To evaluate...

Lewis Wolpert is Professor of Biology as Applied to Medicine at University College London. He originally trained as a civil engineer in South Africa, but changed to research in cell and developmental biology in 1955. His main contributions are related to morphogenesis and his concept of positional information. He was for four years Chairman of the Committee for the Public Understanding of Scien...

The Lewis blood group system comprises two main carbohydrate antigens, Le(a) and Le(b). Lewis typing has traditionally been based on serologic determinations using erythrocytes and saliva. Several recent studies have demonstrated that erythrocyte Lewis phenotype may change during pregnancy or disease, and inappropriate Lewis antigens have been found in both normal and neoplastic tissue. To eval...

Chronic rejection after lung transplantation is manifested as obliterative bronchiolitis (OB). The development of de novo lymphoid tissue (lymphoid neogenesis) may contribute to local immune responses in small airways. Compared with normal lungs, the lung tissue of 13 lung transplant recipients who developed OB demonstrated a significantly larger number of small, airway-associated, peripheral n...