In the past years, halide capping became one of the most promising strategies to passivate the surface of colloidal quantum dots (CQDs) in thin films to be used for electronic and optoelectronic device fabrication. This is due to the convenient processing, strong n-type characteristics, and ambient stability of the devices. Here, we investigate the effect of three counterions (ammonium, methyla...

The synthesis, physical, and spectroscopic properties of a series of metal complexes bridged by the redox-active chloranilate ligand are described. Compounds containing the (CAcat,cat)4- ligand, where (CAcat,cat)4- represents the fully reduced aromatic form of chloranilate, have been prepared by two different routes from H2CA and H4CA starting materials; the corresponding (CAsq,cat)3- analogue ...

The exchange-transferred nuclear Overhauser effect of NMR spectroscopy provides information on small-molecule ligands in association with high-molecular-weight proteins or nucleic acids, or with biomolecular assemblies such as membranes. The method has proved particularly useful for the structural analysis of proton-rich, flexible ligands and for screening mixtures of ligands for binding activi...

Dedicated to Professor Heinrich Nöth on the occasion of his 85th birthday Gold complex [AuCl(NHC)] (NHC = N,N′-dipropylbenzimidazolin-2-ylidene) 1 undergoes facile substitution reactions at the gold(I) center. Treatment of 1 with anionic phenylacetylide or thiophenolate led to the neutral gold complexes 2 and 3, respectively. The cationic gold complexes [Au(NHC)(pyridine)](BF4) [4]BF4 and [Au2(...

2D-IR exchange spectroscopy has been introduced recently to map chemical exchange networks in equilibrium with subpicosecond time resolution. Here, we demonstrate the generalization of 2D-IR exchange spectroscopy to nonequilibrium systems and its application to map light-triggered migration of ligands between different sites in a protein. Within picoseconds after a photodissociating laser pulse...

The trifluoromethylthio group ( SCF3) is a highly privileged modifier for drug molecules. Direct C H trifluoromethylthiolation reactions are highly valuable synthetic tools for the late-stage modification of drug candidates, which have so far been underexplored. We report a palladium-catalyzed ortho-selective mono-trifluoromethylthiolation reaction of arenes. The reaction proceeds through a key...

A ligand exchange HPLC method for enantioseparation of ofloxacin enantiomers was developed by a using C8 stationary phase. Chromatographic separation was performed on a Zorbax-300SB-C8 column eluted with the mobile phase consisting of 15 % methanol in water containing 10mM phenylalanin and 5 mM CuSO4 at flow rate of 0.8 mL/min. The method was simple, rapid and suitable for routine analytical st...

The excited state reactivity of Ru(ii) complexes continues to be a topic of intense investigation because of their widespread use in applications related to solar energy conversion, such as in photoswitches and for medicinal chemistry. In an effort to gain further understanding of photoinduced ligand exchange and isomerization in Ru(ii) complexes, various isomers of the formula [Ru(PTPI)2(CH3CN...

Using a three-phase system, centimeter-scale monolayer gold nanoparticle (Au NP) films have been prepared that have long-range order and hydrophobic ligands. The system contains an interface between an aqueous phase containing Au NPs and an oil phase containing one of various types of amine ligands, and a water/air interface. As the Au NPs diffuse to the water/oil interface, ligand exchange tak...

Despite the fact that many nuclear receptors are ligand dependent, the existence of obligate regulatory ligands is debated for some receptors, including steroidogenic factor 1 (SF-1). Although fortuitously bound bacterial phospholipids were discovered in the structures of the SF-1 ligand-binding domain (LBD), these lipids might serve merely as structural ligands. Thus, we examined whether exoge...