Nanocapsules that can be tailored intelligently and specifically have drawn considerable attention in the fields of drug delivery and bioimaging. Here we conduct a theoretical study on cell uptake of a spherical nanocapsule which is modeled as a linear elastic solid thin shell in three dimensions. It is found that there exist five wrapping phases based on the stability of three wrapping states:...

This paper presents an innovative mixing technology for centrifugal microfluidic platforms actuated using a specially designed flyball governor. The multilayer microfluidic disc was fabricated using a polydimethylsiloxane (PDMS) replica molding process with a soft lithography technique. The operational principle is based on the interaction between the elastic covering membrane and an actuator p...

A method for simulating a two-component lipid bilayer membrane in the mesoscopic regime is presented. The membrane is modeled as an elastic network of bonded points; the spring constants of these bonds are parameterized by the microscopic bulk modulus estimated from earlier atomistic nonequilibrium molecular dynamics simulations for several bilayer mixtures of DMPC and cholesterol. The modulus ...

Abstract-We analyze a three-dimensional frictional contact problem between a homogeneous and isotropic linear elastic body and a substrate consisting of a homogeneous and isotropic linear elastic half-space coated with a transversely isotropic elastic layer. The problem formulation includes the kinematics of the body, including its rolling/sliding on the substrate. Expressions relating the disp...

The difference in the resistance to alkali or acid between collagenous and elastic fibers has been applied to differentiation of the two fibers. However, it is often difficult to keep the arterial elastic membrane intact and to recognize the direction of the artery correctly since the arterial tissue block has been hitherto simply scraped or teased with needles or pincettes in alkaline or acid ...

An elastic analysis of restrained slab strips shows that membrane action enhances serviceability behaviour. However, the enhancement is not as great as for strength and serviceability is critical when membrane action is considered in design. A relatively simple form of non-linear firiite element analysis is developed which is able to model bridge deck behaviour allowing for membrane action. Thi...