The p75 neurotrophin receptor (p75NTR) collaborates with the Nogo receptor (NgR) and LINGO-1 to activate RhoA in response to myelin-based growth inhibitors such as myelin-associated glycoprotein (MAG). In this issue of Neuron, Domeniconi et al., in a surprising turn, show that MAG induces intramembrane proteolysis (RIP) of p75NTR and find that p75NTR cleavage is required for MAG-induced RhoA ac...

Transportation and distribution are the most important elements in work system for any company, which of great importance success chain work. Al-Rabee factory is one largest ice cream factories Iraq it considered productive diversified with products where its cover areas capital Baghdad, however, lacks a based on scientific mathematical methods to transportation processes, moreover, these proce...

We propose a mixed integer non-linear goal programming model for replenishment planning and space allocation in a supermarket in which some constraints on budget, space, holding times of perishable items, and number of replenishments are considered and weighted deviations from two conflicting objectives, namely profitability and customer service level, are minimized. We apply a minimum–maximum ...

The paper describes a new computerized collection of test models for mixed-integer nonlinear programming. Since there is no standard format for nonlinear models, the model collection is augmented with a translation server that can transform the models from their basic GAMS format into a number of other formats such as AMPL, BARON, LINGO, and MINOPT. The translation server can also be used to tr...

Collection of waste is an important logistic activity within any city. In this study, a mathematical model is proposed in order to reduce the cost of waste collection. First a mixed-integer nonlinear programming model is provided including a waste collection routing problem, so that, there is a balance between the distance between trashcans, and the similarity of the trashcans in terms of th...

This paper considers the single machine scheduling problem with precedence constraints and deteriorating jobs. A mathematical model based on binary integer programming (BIP) is developed. By these precedence constraints, jobs can not start before completion of its all predecessors. The represented model is in two steps, in step one the earliest starting time of each job is computed, then the re...

The adoption of smart agricultural technology in rural areas is still limited terms network infrastructure supported. As a result, farmers continue to practice traditional farming that mainly focuses on human labor and requires experience planning the production products unstable weather conditions, which makes highly risky. Currently, long range (LoRa) agriculture support tool will enable Inte...

The Korean Resource Grammar (KRG) is a computational open-source grammar of Korean (Kim and Yang, 2003) that has been constructed within the DELPH-IN consortium since 2003. This paper reports the second phase of the KRG development that moves from a phenomenabased approach to grammar customization using the LinGO Grammar Matrix. This new phase of development not only improves the parsing effici...

LINGOs are a holographic measure of chemical similarity based on text comparison of SMILES strings. We present a new algorithm for calculating LINGO similarities amenable to parallelization on SIMD architectures (such as GPUs and vector units of modern CPUs). We show that it is nearly 3x as fast as existing algorithms on a CPU, and over 80x faster than existing methods when run on a GPU.