19 In this study the feasibility of a LLE-GC-EI-MS method for the analysis of 43 phenolic acids 20 belonging to different chemical structure families which have been described in the literature as 21 microbial-derived metabolites after consumption of dietary polyphenols was proved. In addition, 22 the method was applied for the characterisation of phenolic metabolites resulting from the 23 incu...

OBJECTIVE The purpose of this study was to optimise the HPLC-UV bio-analytical method currently used by the Salamanca University Clinical Hospital for determining lamotrigine plasma levels. MATERIAL AND METHODS The developed HPLC-UV analytic technique currently in use was shown to be linear, exact and precise, and suitable for use in routine monitoring of lamotrigine levels. The drawback of t...

A continuous flow liquid membrane extraction (CFLME)–C18 precolumn-liquid chromatography system was developed for preconcentration and determination of chlorinated phenols (CPs). After preconcentration by CFLME, which is based on the combination of continuous flow liquid–liquid extraction and supported liquid membrane, CPs were enriched in 960 l of 0.5 mol l−1 NaOH used as acceptor. This accept...

Anthocyanins not just have various benefits in food industry but also have been used as natural colourants in cosmetic, coating products and as potential natural photosensitizers in solar cell. Thus, the main purpose of this study was to obtain information on the maximum yield of anthocyanin that can be recovered from Melastoma malabathricum fruit. Factors such as extraction temperature, extrac...

Phthalate esters are endocrine disrupters or mutagens. They are widely used as plasticizers and can be usually found in environmental samples, such as food, soil and polluted air. However, it is difficult to directly determine phthalate esters owing to their relatively low concentration and complex matrices. Therefore, preconcentration and separation have become increasingly important. In recen...

anesthetic agent as well as lidocaine, bupivacaine and mepivacaine (Fig. 1). Unlike bupivacaine and mepivacaine, which are racemic mixtures of the enantiomers containing equal proportion of the (S) and (R) forms, ropivacaine is exclusively the (S)-enantiomer. Since the (R)-enantiomer in the racemic aminoamide has known to be toxic, ropivacaine potentially provides lower toxicity on heart and ce...

A purification method for ochratoxin A, using liquid-liquid extractions and a final cleanup by high-pressure liquid chromatography, is described.

A novel, rapid, simple and sensitive dispersive liquid-liquid microextraction method based on the solidification of floating organic drop (DLLME-SFO) combined with high performance liquid chromatography-ultra violet detection (HPLC-UV) was used to determine acrylamide in potato chips. The derivation of the acrylamide happened in the presence of KBr, KBrO3, H2SO4. Based on studies, 1-undecanol w...