PROBLEM Cytomegalovirus (CMV) infection was previously reported in pregnancy complications. However, its seroprevalence and associated Toll-like receptor (TLR) expression in early-onset preeclampsia (EOPE) with hemolysis, elevated liver enzyme and low platelets syndrome (HELLPs) are unexplored. METHOD OF STUDY A case–control study was performed to examine maternal CMV antibodies, neutrophil T...

: The Cushing syndrome typically presents with abdominal obesity, wide purple striae, glucose intolerance, hypertension, easy bruising, and muscle weakness, a rare disorder interfering ovulation, making the combination of pregnancy less common. Nevertheless, has been reported in pregnancy. Here we report another case syndrome, which merely using literature review at end.

multiple sclerosis (ms) is the most common chronic autoimmune demyelinating disorder of the central nervous system (cns) which preferentially involves young women in early child bearing age. opposite to traditional view emphasized on discouraging female patients from enduring pregnancy, recent investigations showed that pregnancy-related physiological alterations, especially during the third tr...

OBJECTIVE Antiepileptic drugs (AEDs) are commonly prescribed for epilepsy and bipolar disorder but little is known about their use in pregnancy. We examined secular trends in AED prescribing in pregnancy and pregnancy as a determinant for stopping AED prescribing. METHODS We identified 174,055 pregnancies from The Health Improvement Network UK primary care database. Secular trends in AED pres...

Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are two major types of chronic cholestatic liver disease. Each disorder has distinguishing features and variable progression, but both may ultimately result in cirrhosis and hepatic failure. The following offers a review of PBC and PSC, beginning with a general overview of disease etiology, pathogenesis, diagnosis, clinica...

Acute fatty liver of pregnancy (AFLP) is a rare liver disease unique to pregnancy that can lead to acute liver failure. Clinicians must have a high index of suspicion for AFLP because only early diagnosis and prompt delivery improve maternal and fetal prognosis.

Liver damage is the most common complication of anti-tuberculosis drugs, but there is currently no standard prevention for it. The main purpose of this study is to determine the effectiveness of Ziziphus jujuba (Z. jujuba) syrup on the prevention of liver enzyme disorder in TB patients. This study was a protocol for randomized controlled trial. 48 patients were included in the study who were r...

In liver disorder, prothrombin time (PT) is elevated, and fibrinogen level decreased which are considered predictors of increased bleeding risk. We aimed at determining whether increased PT and fibrinogen value reflect the haemostatic potential and bleeding risk in patients with liver disorder. The study comprises a total of 135 subjects including patients with liver disorder (n=75) and healthy...

Growth disorder is an umbrella term for a range of abnormal growth patterns, such as unusually fast or slow growth in infants or children. The causes of growth disorder include hormonal irregularities, chronic disease, complications during pregnancy or genetic conditions. A complex trait such as body size is influenced by multiple genes as well as environmental factors, giving rise to a continu...