In a previous paper (1) we reported that, when livers from rats fed diets containing 2% cholesterol were perfused with whole blood from normal rats, the concentration of cholesterol and triglyceride in the perfusate increased significantly. These lipids were present almost entirely in the lipoproteins of density (d) < 1.019. In the present investigations the transfer of lipids from the liver in...

Excess energy is stored as neutral lipids in lipid droplets (LDs) whose surface is coated by PAT proteins, each playing a distinct cellular function. The adipocyte differentiation-related protein (ADRP) and tail-interacting protein (TIP47) are expressed almost ubiquitously, whereas the oxidative tissue-enriched PAT protein (OXPAT) is expressed in specific tissues, such as the liver. In rat live...

The rise in obesity and diabetes has increased the interest on controlling diet habits. High-fat diet (HFD) and high-carbohydrate diets (HCD) have shown potential benefit for weight management, however their detrimental effects on blood lipids and insulin resistance still remain not well understood. It is known that the macronutrient component of diets is critical for the metabolic control and ...

Ensiling as one of the best methods for utilization of tuna wastes was investigated. docosahexaenoic acid [DHA C22:6(n-3)]- rich products were obtained from the wastes (viscera and dark meat) of four tuna species, namely longtail, skipjack, yellowfin and kawakawa by a procedure involving ensiling in organic acids followed by neutralization. Identification of fatty acids in the samples was perfo...

Ensiling as one of the best methods for utilization of tuna wastes was investigated. docosahexaenoic acid [DHA C22:6(n-3)]- rich products were obtained from the wastes (viscera and dark meat) of four tuna species, namely longtail, skipjack, yellowfin and kawakawa by a procedure involving ensiling in organic acids followed by neutralization. Identification of fatty acids in the samples was perfo...

BACKGROUND Marine derived oils are rich in long-chain polyunsaturated omega-3 fatty acids, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which have long been associated with health promoting effects such as reduced plasma lipid levels and anti-inflammatory effects. Krill oil (KO) is a novel marine oil on the market and is also rich in EPA and DHA, but the fatty acids...

Control of energy metabolism is crucial for optimal functioning of organs and tissues. Amongst all nutrients, glucose is the principal energy source for most cells and, therefore, minimum blood glucose levels must be guaranteed. Alterations in glycaemia can lead to hyperglycaemic states (producing protein glycosylation and toxicity in glucose-sensitive cells) or hypoglycaemic states (that can a...

A tumor model designed to assess liposome-mediated drug delivery to liver has been used in an attempt to better understand the mechanism of activity of liposomal mitoxantrone, a liposomal anticancer drug formulation that appears to be uniquely effective in treating this tumor model. Reductions in liposomal mitoxantrone accumulation in the liver were achieved either by use of poly(ethylene)glyco...

For the purpose to clarify the causes of X-ray disturbances a series of experiments have been conducted on biological and biochemical properties of compound lipids extracted from normal and X-ray irradiated rabbit organs with a special reference to the P-labeled compound lipids uptake, inhibitory action to L cell proliferation and uncoupling of oxidative phosphorylation, and the following resul...

this experiment was conducted to evaluate the effect of silver nanoparticles coated on clinoptilolite on performance traits, liver enzymes and blood lipid concentrations to use 375 cobb 500 broiler chickens in completely randomized design with five treatments and five replicates and 15 birds to each replicate. the use of silver nanoparticles coated on clinoptilolite improved feed conversion rat...