MMICAJmJOURNAL Summary Evidence is presented that a cytopathic agent isolated from human nose, throat, and bronchial swabs, and termed " Ryan virus" is in fact an amoeba of the genus Hartmannella. Detection of a protozoal cell-type by electron microscopy led to the recognition of typical trophozoites and cysts of this free-living soil amoeba in inoculated tissue cultures. Details are given of c...