PURPOSE This study aimed to identify the effectiveness of a newly developed group therapy, called the logo-autobiography program, in improving meaning in life and mental health in the wives of alcoholics. METHODS The program was developed in four steps: literature review, pilot program development, pilot study and detailed program structuring. The pilot program was developed by combining a mo...

G-protein coupled inwardly rectifying potassium channels (GIRKs) are ubiquitously expressed throughout the human body and are an integral part of inhibitory signal transduction pathways. Upon binding of Gβγ subunits released from G-protein coupled receptors (GPCRs), GIRK channels open and reduce the activity of excitable cells via hyperpolarization. As such, they play a role in cardiac output, ...

Two Sample Logo is a procedure for discovery of statistically significant position-specific differences in residue compositions between two multiple sequence alignments, as well as for graphical representation of those differences. It was proposed by Vacic, Iakoucheva and Radivojac [11], and implemented as a web application (available at http://www.twosamplelogo.org) and as a command line progr...