The eye is a complex and highly developed organ which collects light from the surrounding environment, regulates its intensity through a diaphragm, focuses it through an adjustable lens to form an image on retina where this image is converted into a set of electrical signals transmitted to the brain. The eyes are protected in the skull by a bony box called the eye socket (orbit). The wall of th...

"To be what it is, all writing must, therefore be capable of functioning in the radical absence of every empirically determined receiver in general. And this absence is not a continuous modification of presence, it is a rupture in presence, the 'death' or the possibility of the 'death' of the receiver inscribed in the structure of the mark.... What holds for the receiver holds also, for the sam...

Contributing Authors: Douglas Arent (USA), Greg Arrowsmith (Belguim/United Kingdom), Morgan Bazilian (Austria/USA), Lori Bird (USA), Thomas Boermans (Germany), Alex Bowen (United Kingdom), Sylvia Breukers (The Netherlands), Thomas Bruckner (Germany), Sebastian Busch (Austria/Germany), Elisabeth Clemens (Norway), Peter Connor (United Kingdom), Felix Creutzig (Germany), Peter Droege (Liechtenstei...

Birder, Lori A. More than just a barrier: urothelium as a drug target for urinary bladder pain. Am J Physiol Renal Physiol 289: F489–F495, 2005; doi:10.1152/ ajprenal.00467.2004.—Although the urinary bladder urothelium has classically been thought of as a passive barrier to ions/solutes, a number of novel properties have been recently attributed to these cells. Studies have revealed that the ur...

Disclosure The views and opinions expressed in the News of the Academy of Neonatal Nursing are those of the contributing editors and do not necessarily reflect those of the Academy of Neonatal Nursing. The Academy of Neonatal Nursing is not responsible for products, programs, or links mentioned in these pages. They are provided as a convenience and should not be viewed, in any way, as an endors...

Isom, Lori L. Pathobiology of Visceral Pain: Molecular Mechanisms and Theraputic Implications. I. Cellular and molecular biology of sodium channel b-subunits: therapeutic implications for pain? Am. J. Physiol. Gastrointest. Liver Physiol. 278: G349–G353, 2000.—Voltage-gated sodium channel a-subunits have been shown to be key mediators of the pathophysiology of pain. The present review considers...