Libman-Sacks endocarditis (LSE) is a common manifestation of valve disease in antiphospholipid syndrome. Mitral valve LSE is characterized by verrucous vegetations on the atrial surfaces of valve leaflets. In this report, mitral valve LSE was visualized by real time 3D transesophageal echocardiography (TEE). 3D TEE provides a unique en face view of the mitral valve akin to a surgical or autopsy...

A pixel in remotely sensed hyperspectral imagery is typically a mixture of multiple electromagnetic radiances from various ground cover materials. Spectral unmixing is a quantitative analysis procedure used to recognize constituent ground cover materials (or endmembers) and obtain their mixing proportions (or abundances) from a mixed pixel. The abundances are typically estimated using the least...

Pigmentary changes of the skin can negatively impact quality life and are challenging to treat. A successful correction hyperpigmentary conditions may involve modulation multiple stages melanogenesis. We identified two bisbenzylisoquinoline alkaloid compounds enriched in lotus sprout extract (LSE) impacting an underappreciated component melanin lifecycle, melanosomal autophagocytosis.In vitrost...

The Role of Funding and Policies on Innovation in Cancer Drug Development P Kanavos, PhD, Senior Lecturer in international health policy, R Sullivan, PhD, MD, Chairman, G Lewison, PhD, MD, W Schurer, MSc, Research Officer, S Eckhouse, Chief Projects Officer, Z Vlachopioti, MSc, Research Assistant LSE Health, Department of Social Policy, London School of Economics. European Cancer Research Manag...

Research on the list strength effect (LSE) has shown that learning some words on a list more strongly than others impairs memory for the weakly learned words when tested with a recall task. Norman (2002) demonstrated that the LSE also occurs within the recollection process of a recognition test. In this study, a mechanistic dual-process account of the LSE was tested that simultaneously makes pr...

This paper describes the development of a Spanish-Spanish Sign Language (LSE) translation system. Firstly, it describes the first Spanish-Spanish Sign Language (LSE) parallel corpus focused on two specific domains: the renewal of the Identity Document and Driver’s License. This corpus includes more than 4,000 Spanish sentences (in these domains), their LSE translation and a video for each LSE s...

Abstract: We consider the problem of estimating an unknown n1×n2 matrix θ∗ from noisy observations under the constraint that θ∗ is nondecreasing in both rows and columns. We consider the least squares estimator (LSE) in this setting and study its risk properties. We show that the worst case risk of the LSE is n−1/2, up to multiplicative logarithmic factors, where n = n1n2 and that the LSE is mi...

Libman-Sacks Endocarditis (LSE) is a form of nonbacterial thrombotic endocarditis (NBTE) occurring in the set­ting hypercoagulable states like solid organ malignancies, systemic lupus erythematosus (SLE) and primary or secondary antiphospholipid antibody syndrome (APLS).LSE most characteristic cardiac manifestation SLE. Even though incidence clinically significant valve dysfunction embolic phen...