Neuroblastoma (NB) is considered one of the malignant tumors of the nervous system which originates from primordial neural crest cell and is known as the most common extra-cranial solid tumor in childhood. This tumor which is often intra-abdominal, metastases in various sites including the skull, long bones, liver, bone marrow and lymph nodes, but lung metastasis at initial diagnosis is rare (0...

colorectal cancer most commonly metastasizes to the liver and lung. metastatic colon carcinoma (mcc) to the breast is extremely rare. krukenberg tumor is an uncommon metastatic tumor of the ovary. case presentation: a 38 years woman presented with abdominal pain. in evaluation colon cancer was diagnosed at stage 3. folfox chemotherapy was done. after one year she developed krukenberg tumor. few...

PURPOSE To study the interfraction reproducibility of breath-holding using active breath control (ABC), and to develop computerized tools to evaluate three-dimensional (3D) intrathoracic motion in each patient. METHODS AND MATERIALS Since June 2002, 11 patients with non-small-cell lung cancer enrolled in a Phase II trial have undergone four CT scans: one during free-breathing (reference) and ...

PURPOSE To develop a tumor tracking method based on a surrogate-driven motion model, which provides noninvasive dynamic localization of extracranial targets for the compensation of respiration-induced intrafraction motion in high-precision radiation therapy. METHODS AND MATERIALS The proposed approach is based on a patient-specific breathing motion model, derived a priori from 4-dimensional p...

Purpose: To develop and validate an automatic algorithm for the detection and functional assessment of lung tumors on three-dimensional respiratory gated PET/CT images. Method and Materials: First the algorithm will automatically segment lung regions in CT images, then identify and localize focal increases of activity in lung regions of PET images at each gated bin. Once the tumor voxels have b...

background: in radiation treatment of moving targets located in thorax region of patient body, the delivered dose does not match with the planned treatment, resulting in some over and under dosage in the tumor volume, as a function of motion magnitude and frequency. several efforts have been done to investigate the target motion effects on dose distribution in the target and surrounding normal ...

Feline herpesvirus is an extremely widespread cause of eye and respiratory disease in cats. Some estimate that over 90% of cats have been exposed to herpesvirus, and half of those continue to shed virus intermittently. Half of those shedding may have recurrent eye problems, some of which are painful and blinding. Treatment has been frustrating as there is a wide spectrum of disease and suscepti...

The purpose of this study was to validate the dose prescription defined to the gross tumor volume (GTV) 3D and 4D dose distributions of stereotactic radiotherapy for lung cancer. Treatment plans for 94 patients were generated based on computed tomography (CT) under free breathing. A uniform margin of 8 mm was added to the internal target volume (ITV) to generate the planning target volume (PTV)...