Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with the human malignancy Kaposi's sarcoma and the lymphoproliferative disorders primary effusion lymphoma and multicentric Castleman's disease. KSHV establishes lytic infection of monocytes in vivo, which may represent an important cellular reservoir during KS disease progression. KS tumors consist of latently infected endothelial ce...

purpose: to report a case of metastatic tumor to the right upper eyelid originating from a lung adenocarcinoma without any systemic signs. case report: a 68-year-old man had a two-month history of painless swelling in the right upper eyelid. the tumor slowly grew. two years before his presentation, he had received chemotherapy for lung cancer for one year. systemic and ocular examinations were ...

trauma is the most common reason in 1-34 years olds. in patient with multiple traumas, the head is the most common involved part. the importance of computed tomography (ct scan) in diagnosis of brain trauma is well established and ct of the brain is a choice method. finding lesion in brain traumatic patient is very important so goal of this study is finding of brain ct scan in traumatic patient...

introduction: the aim of this study was to identify the reasons for failure in clinical, radiographic, and histopathologic diagnoses as well as their interactions with each other. methods: personal information and lesion characteristics of 51 patients with central or peripheral exophytic lesions were collected in mashhad dental school. specialists determined clinical and radiographic diagnoses ...

Malignant Catarrhal Fever (MCF) is a fatal lymphoproliferative disease of cattle and other ungulates caused by alcelaphine herpesvirus 1 (AlHV-1) ovine 2 (OvHV-2), the main causative agents wildebeest-associated MCF (WA-MCF) sheep-associated (SA-MCF), respectively. The virus mainly spread aerosols from pregnant or newborn sheep, goats, wildebeest to susceptible animals. This case report present...

RATIONALE Conjunctival lymphoproliferative lesions constitute a significant diagnostic challenge and it is essential to exclude neoplastic lesions. Histopathological and immunohistochemical tests are very useful in establishing the correct diagnosis. Reactive lymphoid hyperplasia (RLH) is part of a spectrum of lymphocytic infiltrative disorders. Evidence is scarce regarding appropriate treatmen...

Cutaneous pseudolymphoma (C-PSL) is defined as reactive polyclonal benign lymphoproliferative process predominantly composed of either B-cells or T-cells, localized or disseminated. It heals spontaneously after cessation of the causative factor (e.g. drugs) or after non-aggressive treatment. The author herein presents a case of C-PSL with an immunohistochemical study. A 78-year-old man consulte...

Post-transplant lymphoproliferative disease (PTLD) describes a heterogenous group of lymphoproliferative diseases, occurring as a result of uncontrolled B cell proliferation in the context of post-transplant immunosuppression. The incidence depends on the type of transplant and immunosuppression used; the median time to onset is shorter for recipients of stem cell transplants (2 months) than th...

Guideline update and changes: This guideline is an updated version of the 2008 guideline, revised to take into account the 2008 WHO guidelines as they apply to the lymphoproliferative disorders. There have been no changes to the sections on histiocytic and dendritic cell neoplasms. The pathology of posttransplant lymphoproliferative disorder is dealt with in the BCSH guideline on this topic. Th...

IL-6, a multifunctional cytokine produced by monocytes, fibroblasts, and endothelial cells, promotes the growth of EBV-immortalized B cells in vitro and renders these cells tumorigenic in athymic mice. In the present study, serum/plasma IL-6 bioactivity was found to be abnormally elevated, albeit transiently, in 17 of 18 solid organ transplant recipients with posttransplant lymphoproliferative ...